Liver cancer mortality statistics

Deaths

Deaths from liver cancer, 2016, UK

 

Proportion of all deaths

Percentage liver cancer is of total cancer deaths, 2016, UK

 

Age

Peak rate of liver cancer deaths, 2014-2016, UK

 

Trend over time

Change in liver cancer mortality rates since the early 1970s, UK

Liver cancer is the 8th most common cause of cancer death in the UK, accounting for 3% of all cancer deaths (2016).[1-3]

In males in the UK, liver cancer is the 8th most common cause of cancer death (4% of all male cancer deaths). In females in the UK it is the 11th most common cause of cancer death (3% of all female cancer deaths).

60% of liver cancer deaths in the UK are in males, and 40% are in females.

Liver cancer mortality rates (European age-standardised (AS) rates Open a glossary item ) for persons are significantly higher than the UK average in Scotland, and similar to the UK average in all other UK constituent countries.

Liver Cancer (C22), Number of Deaths, Crude and European Age-Standardised (AS) Mortality Rates per 100,000 Population, UK, 2016

  England Scotland Wales Northern Ireland UK
Male Deaths 2641 373 171 87 3272
Crude Rate 9.7 14.2 11.1 9.5 10.1
AS Rate 11.6 16.6 12.0 12.9 12.0
AS Rate - 95% LCL 11.1 14.9 10.2 10.2 11.6
AS Rate - 95% UCL 12.0 18.2 13.8 15.7 12.4
Female Deaths 1749 211 109 76 2145
Crude Rate 6.3 7.6 6.9 8.0 6.4
AS Rate 6.2 7.4 6.2 8.7 6.4
AS Rate - 95% LCL 6.0 6.4 5.1 6.8 6.1
AS Rate - 95% UCL 6.5 8.4 7.4 10.7 6.7
Persons Deaths 4390 584 280 163 5417
Crude Rate 7.9 10.8 9.0 8.8 8.3
AS Rate 8.7 11.3 8.8 10.6 8.9
AS Rate - 95% LCL 8.4 10.4 7.8 9.0 8.7
AS Rate - 95% UCL 8.9 12.3 9.9 12.3 9.2

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item  around the AS Rate Open a glossary item 
 

For liver cancer mortality differences between countries largely reflect differences in incidence.

References

  1. Data were provided by the Office for National Statistics on request, October 2017. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, December 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2016, ICD-10 C22.

Last reviewed:

Liver cancer mortality is strongly related to age, with the highest mortality rates being in older people. In the UK in 2014-2016, on average each year half (50%) of deaths were in people aged 75 and over.[1-3] This largely reflects higher incidence and lower survival for liver cancer in older people.

Age-specific mortality rates rise steadily from around age 45-49 and more steeply from around age 60-64. The highest rates are in the 85 to 89 age group for males and females.

Mortality rates are significantly higher in males than females in a number of (mainly older) age groups. The gap is widest at age 60 to 64, when the age-specific mortality rate is 2.3 times higher in males than females.

Liver Cancer (C22), Average Number of Deaths per Year and Age-Specific Mortality Rates per 100,000 Population, UK, 2014-2016

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item around the AS Rate Open a glossary item

References

  1. Data were provided by the Office for National Statistics on request, October 2017. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp
  3. Data were provided by the Northern Ireland Cancer Registry on request, December 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

 

About this data

Data is for UK, 2014-2016, ICD-10 C22.

Last reviewed:

Liver cancer European age-standardised (AS) Open a glossary item mortality rates for males and females combined increased by 209% in the UK between 1971-1973 and 2014-2016.[1-3] The increase was of a similar size in males and females.

For males, liver cancer AS mortality rates in the UK increased by 202% between 1971-1973 and 2014-2016. For females, liver cancer AS mortality rates in the UK increased by 199% between 1971-1973 and 2014-2016.

Over the last decade in the UK (between 2004-2006 and 2014-2016), liver cancer AS mortality rates for males and females combined increased by 55%. In males AS mortality rates increased by 51%, and in females rates increased by 58%.

Liver Cancer (C22), European Age-Standardised Mortality Rates per 100,000 Population, UK, 1971-2016

For most cancer types, mortality trends largely reflect incidence and survival trends. For example, rising mortality may reflect rising incidence and stable survival, while falling mortality may reflect rising incidence and rising survival.

Liver cancer mortality rates have increased overall in all broad adult age groups in males and females combined in the UK since the early 1970s.[1-3] Rates in 25-49s have increased by 45%, in 50-59s have increased by 106%, in 60-69s have increased by 186%, in 70-79s have increased by 225%, and in 80+s have increased by 313%.

Liver Cancer (C22), European Age-Standardised Mortality Rates per 100,000 Population, By Age, UK, 1971-2016

References

  1. Data were provided by the Office for National Statistics on request, October 2017. Similar data can be found here: http://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths.
  2. Data were provided by ISD Scotland on request, October 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Northern Ireland Cancer Registry on request, December 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1971-2016, ICD-10 C22.

Last reviewed:

Liver cancer mortality rates are projected to rise by 58% in the UK between 2014 and 2035, to 16 deaths per 100,000 people by 2035.[1] This includes a larger increase for males than for females.

For males, liver cancer European age-standardised (AS) Open a glossary item mortality rates in the UK are projected to rise by 57% between 2014 and 2035, to 22 deaths per 100,000 by 2035.[1] For females, rates are projected to rise by 53% between 2014 and 2035, to 11 deaths per 100,000 by 2035.[1]

Liver cancer (C22), Observed and Projected Age-Standardised Mortality Rates, by Sex, UK, 1979-2035

 

It is projected that 12,179 deaths from liver cancer (7,449 in males, 4,730 in females) will occur in the UK in 2035.

References

  1. Smittenaar CR, Petersen KA, Stewart K, Moitt N. Cancer Incidence and Mortality Projections in the UK Until 2035. Brit J Cancer 2016.

About this data

Data is for: UK, 1979-2014 (observed), 2015-2035 (projected), ICD-10 C22

Projections are based on observed incidence and mortality rates and therefore implicitly include changes in cancer risk factors, diagnosis and treatment. It is not possible to assess the statistical significance of changes between 2014 (observed) and 2035 (projected) figures. Confidence intervals are not calculated for the projected figures. Projections are by their nature uncertain because unexpected events in future could change the trend. It is not sensible to calculate a boundary of uncertainty around these already uncertain point estimates. Changes are described as 'increase' or 'decrease' if there is any difference between the point estimates.

More on projections methodology

Last reviewed:

There is evidence for a strong association between liver cancer mortality and deprivation for both males and females in England.[1] England-wide data for 2007-2011 show European age-standardised Open a glossary item mortality rates are 100% higher for males living in the most deprived areas compared with the least deprived, and 72% higher for females.[1]

Liver Cancer (C22), European Age-Standardised Mortality Rates by Deprivation Quintile, England, 2007-2011

The estimated deprivation gradient in liver cancer mortality between people living in the most and least deprived areas in England has not changed in the period 2002-2011.[1] It has been estimated that there would have been around 600 fewer cancer deaths each year in England during 2007-2011 if all people experienced the same mortality rates as the least deprived.[1]

Reference

  1. Cancer Research UK and National Cancer Intelligence Network. Cancer by deprivation in England: Incidence, 1996-2010, Mortality, 1997-2011. London: NCIN; 2014.

About this data

Data is for: UK, 2007-2011, ICD-10 C22

Deprivation gradient statistics were calculated using mortality data for 2007-2011. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

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