Recently funded awards

This page lists the investigator-led programmes, projects and fellowships that we have recently supported through our response-mode grant funding schemes.

Select a funding committee to see what they have funded to date in 2021 (as of July 2021):

Biomarker Project Awards

Professor Mhairi Copland, University of Glasgow
Evaluation of key Biomarkers for the prediction of successful treatment-free remission (TFR) in chronic myeloid leukaemia

Professor Anthony Moorman, Newcastle University
Evaluating integrated and multi-biomarker driven risk stratification in paediatric acute lymphoblastic leukaemia 

Clinical Trial Awards

Professor Darren Hargrave and Professor Pamela Kearns, University of Birmingham 
LOGGIC- Phase III, randomised, international multicentre trial for children and adolescents with low-grade glioma

Dr Christopher Fox, University of Southampton
Optimizing MATrix as remission induction treatment for newly diagnosed primary CNS Lymphoma – a randomized phase III trial (OPTIMATE trial)

Professor Peter Hoskin, Professor Gareth Griffiths & Ananya Choudhury, University of Southampton 
CRAIN: A phase 1b clinical trial with dose escalation and dose expansion phases of ASTX660 in combination with standard radical radiotherapy in cervical cancer with chemoradiation

Dr Victoria Coyle and Professor Daniel Longley, University of Glasgow 
ASTFOX: A Phase I study of the IAP antagonist, ASTX660, in combination with standard of care FOLFOX chemotherapy in metastatic colorectal cancer

Mr Dirk Strauss, The Royal Marsden NHS Foundation Trust
EORTC-1809-STBSG: A randomised phase III study of neoadjuvant chemotherapy followed by surgery versus surgery alone for patients with High Risk RetroPeritoneal Sarcoma (STRASS 2)

Professor Simon Crabb and Professor Gareth Griffiths, University of Southampton
AURORA: Atezolizumab in patients with squamous cell carcinoma of the bladder and urinary tract – a single arm, open label, multicentre, phase II trial

Dr Juanita Lopez, Professor Christina Yap and Professor Pascal Meier, Institute of Cancer Research
ASTEROID – A Phase I proof of concept study of ASTX660 in combination with PEmbROlizumab:utilizing triple IAP blockade as a strategy to maximize Immunogenic cell Death and the generation of a efficient adaptive immune response

Professor Jonathan Bridgewater, University College London 
SAFIR-ABC10: molecular screening for precision medicine in advanced biliary cancers

Professor Bernadette Brennan and Professor Pamela Kearns, University of Birmingham 
International clinical research programme to improve outcomes in newly diagnosed Ewing Sarcoma – Trial 1 (INTER-EWING-1)

Professor Gladstone (Amos) Burke and Professor Lucinda Billingham, University of Birmingham 
Glo-BNHL: A Global Study of Novel Agents in Relapsed and Refractory B-NHL 

Extension

Dr Martin McCabe and Professor Keith Wheatley, University of Birmingham 
rEECur: International Randomised Controlled Trial of Chemotherapy for the Treatment of Recurrent and Primary Refractory Ewing Sarcoma

Prospective Sample Collection Awards

Professor Paul Lorigan, University of Manchester 
From primary diagnosis to relapse or cure; a comprehensive sample collection from patients with stage II melanoma

​​Programme Awards

New Programmes

Professor Christian Speck, Imperial College London 
Discovering the structural and mechanistic principles of human helicase-loading control and its misregulation in cancer

Professor Trevor Graham, Queen Mary, University of London 
MECCA: Metastatic Evolutionary dynamics of Colorectal Cancer

Dr Vincenzo D’Angiolella, Professor Steve Clifford & Professor Alex Bullock, University of Oxford/Newcastle University 
The neomorphic role of KBTBD4 in medulloblastoma

Renewing Programmes

Professor Sergio Quezada, University College London
Development and evaluation of T- and innate-cell engagers driving agonistic activity independent of Fc/FcReceptor interactions

Professor Martin Humphries, University of Manchester
Stromal rigidity as a driver of pancreatic ductal adenocarcinoma progression

Programme Foundation Awards

Dr Marc Mansour, University College London 
Dissecting and exploiting enhancer dysregulation in T-cell acute lymphoblastic leukaemia

Dr Dirk Sieger, University of Edinburgh 
The role of microglia during the formation of neural network-like connections in glioma

Multidisciplinary Project Awards

Professor Darryl Overby & Professor Iain McNeish, Imperial College London 
A “top-down” organ-on-chip approach for personalised medicine in ovarian cancer

Dr Iain Dunlop, Imperial College London
Biophysical design of immunomodulatory nanotherapeutics

Early Detection and Diagnosis Programme Awards

George Hanna, Imperial College London
Augmented Response of vOlatile bioMarkers to detect oesophagogastric Adenocarcinoma (AROMA)

Early Detection and Diagnosis Project Awards

Clare Rebbeck and Gregory Hannon, University of Cambridge
Using a “Timeline of DCIS progression” to create an improved clinical assay for breast cancer risk 

Francesca Palombo, Nick Stone and Oliver Old, University of Exeter
Development of advanced optical tools for early detection and diagnosis of oesophageal cancer with high mechanical and chemical specificity 

Maria Kyrgiou and Zoltan Takats, Imperial College London
High-throughput laser-assisted Rapid Evaporative Ionisation Mass Spectrometry (Laser-REIMS) in the early detection and diagnosis of cervical pre-invasive disease

Early Detection and Diagnosis Primer Awards

Charlene Greenwood, University of Keele
Prostate Cancer: High Accuracy Early Diagnosis based on Tissue Microenvironments

Adam Creamer and Leah Frenette, Imperial College London
Magnetic, Fluorescent Nanoparticles for the Isolation of Blood Biomarkers in the Early Detection of Pancreatic Cancer

Lesely Smith and Richard Neal, University of Leeds
Development of a myeloma case-finding approach for higher-risk patients: analysis of routine blood tests

Jason Webber, Swansea University
Extracellular Vesicle Glycoproteins for Prostate Cancer Diagnosis (EVGlyProD)

David Westhead, University of Leeds
Prediction of Early Progression in Follicular Lymphoma

Oluwafunmilola Ola and Frankie Rawson, University of Nottingham
Point-of-care-Based Electrochemical Sensing for Human Papillomavirus Detection

Jamie Blundell, University of Cambridge
Exploiting the Immune System for Early Cancer Detection

Richard Mair and Rohitashwa Sinha, University of Cambridge
Early Detection with Urine and Cognitive Assessment Multiplex (The EDUCAM study)

Marc Moncrieff, Stuart Rushworth, Mona Saad, Norfolk and Norwich University Hospital NHS Trust
Feasibility study investigating circulating peripheral mitochondrial DNA as a potential non-invasive biomarker for diagnosis and surveillance of high risk cutaneous melanoma

Christopher Toseland, University of Sheffield
Single molecule mass photometry for the early detection of cancer

Sourav Banerjee, University of Dundee
Secreted phosphoproteome in blood as early detection and risk stratification biomarkers of glioma

Project Grants

Professor Paul Pharoah, University of Cambridge 
Rare germline genetic variation in the coding and non-coding genome and susceptibility to ovarian cancer

Dr Hannah Sallis, University of Bristol 
Smoking behaviours and transitions to vaping in early adulthood: Investigating predictors with longitudinal data

Career Development Fellowship

Dr Thomas MacVicar, CRUK Beatson Institute, Glasgow 
Targeting mitochondrial metabolite transport in pancreatic cancer

Dr Diu Nguyen, Queen Mary, University of London 
Targeting post-transcriptional regulators to eradicate leukemic stem cells in acute myeloid leukemia

Clinician Scientist Fellowship

Dr Sally George, Institute of Cancer Research 
The role of ATRX alterations in the genesis and therapeutic sensitivity of neuroblastoma

Dr Marwan Kwok, University of Birmingham
Identifying tumour-immune interactions as determinants of clinical sequelae in chronic lymphocytic leukaemia

Pre-doctoral Research Bursaries

Dr Louisa Harding-Edgar, University of Glasgow 
Lung cancer and early diagnosis after Covid-19: identifying the impact of remote consulting on lung cancer referral

Dr Tom Andrew, Newcastle University 
Optimising deep learning models for risk classification of AMBLor in cutaneous melanoma

Mr Jonathan Pushpa-Rajah, University of Cambridge
Use of structural variants to detect recurrence of renal cancer via blood

Dr Alexandros Rampotas, University College London
Towards developing a Chimeric Antigen Receptor (CAR) construct against mutated calreticulin

Postdoctoral Research Bursaries

Dr Elizabeth Maughan, Institute of Child Health/UCL
Generating personalised preclinical models for advanced paediatric thyroid cancer

More facts and figures about our research funding

Facts and figures about our research funding

Find out more about how and where we supported research in the last year with our interactive map and infographics.

Funding committees

Successful applicant case studies

Find out how our current grantees successfully applied for funding.

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