In situ breast carcinoma incidence statistics

Cases

New cases of in situ breast carcinoma, 2015, UK

 

Age

Peak rate of in situ breast carcinoma cases, 2013-2015, UK

Trend over time

Change in in situ breast cancer incidence rates since the early 1990s, UK

Breast carcinoma in situ incidence rates (European age-standardised (AS) rates Open a glossary item ) for persons are significantly lower than the UK average in Scotland and Wales, and similar to the UK average in all other UK constituent countries. [1-4]

Breast Carcinoma In Situ (D05), Number of New Cases, Crude and European Age-Standardised (AS) Incidence Rates per 100,000 Population, UK, 2015

  England Scotland Wales Northern Ireland UK
Male Cases 22 4 1 2 29
Crude Rate 0.1 0.2 0.1 0.2 0.1
AS Rate 0.1 0.2 0.1 0.2 0.1
AS Rate - 95% LCI 0.1 0.0 -0.1 -0.1 0.1
AS Rate - 95% UCI 0.1 0.4 0.2 0.6 0.1
Female Cases 6,832 462 345 234 7,873
Crude Rate 24.6 16.7 21.9 24.8 23.8
AS Rate 25.7 16.4 21.3 27.0 24.7
AS Rate - 95% LCI 25.1 14.9 19.0 23.6 24.2
AS Rate - 95% UCI 26.3 17.9 23.5 30.5 25.2
Persons Cases 6,854 466 346 236 7,902
Crude Rate 12.5 8.7 11.2 12.7 12.1
AS Rate 13.3 8.6 11.0 14.1 12.8
AS Rate - 95% LCI 13.0 7.8 9.9 12.3 12.5
AS Rate - 95% UCI 13.6 9.4 12.2 15.9 13.1

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item  around the AS Rate Open a glossary item 
 

For breast cancinoma in situ, like most cancer types, differences between countries largely reflect risk factor prevalence in years past.

References

  1. Data were provided by the Office for National Statistics on request, July 2017. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, August 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence anwd Surveillance Unit, Health Intelligence Division, Public Health Wales on request, October 2017. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, July 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2015, ICD-10 D05.

Last reviewed:

Breast carcinoma in situ incidence is related to age, with the highest incidence rates being in the 65 to 69 age group. In the UK in 2013-2015, on average each year around a tenth (9%) of new cases were in people aged 75 and over.[1-4

Age-specific incidence rates in males increase from age 35-39 and decrease in the oldest age groups. In females, rates rise steeply from around age 35-39, then decrease steeply from age 65-69 and decrease steadily from age 75-79. The highest rates are in the 80 to 84 age group for males and the 65 to 69 age group for females.

Incidence rates are significantly lower in males than females in a number of (mainly older) age groups. The gap is widest at age 50 to 54, when the age-specific incidence rate is 487 times lower in males than females.

Breast Carcinoma In Situ (D05), Average Number of New Cases per Year and Age-Specific Incidence Rates per 100,000 Population, Females, UK, 2013-2015

95% LCL and 95% UCL are the 95% lower and upper confidence limits Open a glossary item  around the AS Rate Open a glossary item
 

For in situ breast carcinoma, most cases are identified through the breast cancer screening programme. Incidence increases rapidly at the age screening starts, as prevalent cases are identified, then falls rapidly at the age routine screening ends.

References

  1. Data were provided by the Office for National Statistics on request, July 2017. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, August 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, October 2017. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, July 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 2013-2015, ICD-10 D05.

Last reviewed:

Breast carcinoma in situ European age-standardised (AS) Open a glossary item incidence rates for males and females combined increased by 186% in the UK between 1993-1995 and 2013-2015.[1-4] The increase was larger in females than in males.

For males, breast carcinoma in situ AS incidence rates in the UK increased by 80% between 1993-1995 and 2013-2015. For females, breast carcinoma in situ AS incidence rates in the UK increased by 187% between 1993-1995 and 2013-2015.

Over the last decade in the UK (between 2003-2005 and 2013-2015), breast carcinoma in situ AS incidence rates for males and females combined increased by 46%.[1-4] In males AS incidence rates remained stable, and in females rates increased by 47%.

Breast Carcinoma In Situ (D05), European Age-Standardised Incidence Rates, Females, UK, 1993-2015

Breast carcinoma in situ incidence rates have increased overall in all broad adult age groups in females in the UK since the early 1990s.[1-4] Rates in 25-49s have increased by 172%, in 50-64s have increased by 112%, in 65-69s have increased by 600%, in 70-79s have increased by 450%, and in 80+s have increased by 424%.

Breast Carcinoma In Situ (D05), European Age-Standardised Incidence Rates, By Age, Females, UK, 1993-2015

References

  1. Data were provided by the Office for National Statistics on request, July 2017. Similar data can be found here: https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/cancerregistrationstatisticsengland/previousReleases.
  2. Data were provided by ISD Scotland on request, August 2017. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit, Health Intelligence Division, Public Health Wales on request, October 2017. Similar data can be found here: http://www.wcisu.wales.nhs.uk.
  4. Data were provided by the Northern Ireland Cancer Registry on request, July 2017. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/.

About this data

Data is for UK, 1993-2015, ICD-10 D05.

Last reviewed:

Most in situ breast carcinoma cases are intraductal, and there is a much smaller proportion of lobular in situ breast carcinomas (2010-2012).[1-4]

A small proportion of cases did not have the specific part of the breast recorded in cancer registry data.[1-4]

Cases and percentages may not sum due to rounding

References

  1. Data were provided by the Office for National Statistics on request, July 2014. Similar data can be found here: http://www.ons.gov.uk/ons/rel/vsob1/cancer-statistics-registrations--england--series-mb1-/index.html.
  2. Data were provided by ISD Scotland on request, April 2014. Similar data can be found here: http://www.isdscotland.org/Health-Topics/Cancer/Publications/index.asp.
  3. Data were provided by the Welsh Cancer Intelligence and Surveillance Unit on request, April 2014. Similar data can be found here: http://www.wales.nhs.uk/sites3/page.cfm?orgid=242&pid=59080.
  4. Data were provided by the Northern Ireland Cancer Registry on request, June 2014. Similar data can be found here: http://www.qub.ac.uk/research-centres/nicr/CancerInformation/.

About this data

Data is for UK, 2010-2012, ICD-10 D05.

Last reviewed:

A quarter of women diagnosed with in situ breast carcinoma in England during 2006-2007 live in the least deprived areas of England, while only 13% live in the most deprived areas.[1] A similar distribution of cases by deprivation is also reported for invasive breast cancer.[1]

References

  1. West Midlands Cancer Intelligence Unit. The Non-Invasive Breast Cancer report: An analysis of non-invasive breast cancers diagnosed in England from 1 January 2006 to 31 December 2007. National Cancer Intelligence Unit, 2011. 

About this data:

Data is for UK, 2002-2006 and 2007-2011, ICD-10 D05

Deprivation gradient statistics were calculated using mortality for two time periods: 2002-2006 and 2007-2011. The 1997-2001 mortality data were only used for the all cancers combined group as this time period includes the change in coding from ICD-9 to ICD-10. The deprivation quintiles were calculated using the Income domain scores from the Index of Multiple Deprivation (IMD) from the following years: 2004, 2007 and 2010. Full details on the data and methodology can be found in the Cancer by Deprivation in England NCIN report.

Last reviewed:

The proportion of incidence cases in White females with in situ breast carcinoma is significantly higher than for Asian or Black females.[1]

A similar ethnic profile is also reported for invasive breast cancer.[2]

Analysis included unknown data. For in situ breast carcinoma, 5,460 cases were identified; 28% had no known ethnicity.

References

  1. West Midlands Cancer Intelligence Unit. The Non-Invasive Breast Cancer report: An analysis of non-invasive breast cancers diagnosed in England from 1 January 2006 to 31 December 2007 (PDF 342KB). National Cancer Intelligence Unit, 2011. 
  2. National Cancer Intelligence Network (NCIN) and Cancer Research UK. Cancer Incidence and Survival by Major Ethnic Group, England, 2002-2006. London: NCIN; 2009.

About this data

Data is for England, 2006-2007, ICD-O2 & ICD-O3

Last reviewed:

An estimated 63,800 women who had been diagnosed with in situ breast carcinoma between 1991 and 2010 were alive in the UK at the end of 2010.[1]

References

  1. Macmillan Cancer Support and National Cancer Registration and Analysis Service. Cancer Prevalence UK Data Tables. London: NCRAS; 2015.

About this data

Data is for: Great Britain (1991-2010) and Northern Ireland (1993-2010), ICD-10 D05

Last reviewed:

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