Recently funded awards

This page lists the investigator-led programmes, projects and fellowships that we have recently supported through our response-mode grant funding schemes.

Select a funding committee to see what they have funded to date in 2022-23 (for Grant Award Letters issued up to July 2023):

July 2023


Prospective Sample Collection Awards

Dr Anna Wilkins and Professor Emma Hall (Institute of Cancer Research)

3P sample collection application

Dr Ann Henry, Dr Finbar Slevin, Dr Alexandra Clipson (University of Leeds)

POINTER-PC SC: Evaluating molecular markers of radiotherapy efficacy and toxicity for pelvic nodal recurrence in prostate cancer

Dr Christopher Williams and Professor Andrew Beggs (University of Leeds)

ctDNA collection within the ARIEL trial: A biomarker enrichment trial of anti-EGFR agents in right primary tumour location, RAS wild-type, advanced colorectal cancer (aCRC)

Clinical Trial Awards

Professor Gordon Jayson and Professor Richard Adams (University of Manchester)

VALTIVE1b: Validation of Tie2 for VEGF inhibitors in Patients With Ovarian Cancer Treated With Olaparib and Bevacizumab Maintenance Therapy: Optimising the Design (Costed Extension)

Professor Michael Schmid, Professor Paula Ghaneh, Dr Ainhoa Mielgo, Professor Daniel Palmer (University of Liverpool)

Investigating the translational potential of inhibiting AXL in combination with adjuvant chemotherapy in the treatment of pancreatic cancer. (Pre-Clinical Package)

Experimental Medicine Awards

Professor Louis Chesler, Professor Darren Hargrave and Dr Isidro Cortés-Ciriano (Institute of Cancer Research)

Stratified Medicine Paediatrics 2 (StratMedPaediatrics2)

March 2023

Clinical Trial Awards

Professor Darren Hargrave, University of Birmingham

CRUK/23/002: BIOMEDE 2.0: Biological Medicine for Diffuse Intrinsic Pontine Glioma (DIPG) Eradication

Dr Reuben Benjamin, Professor Christina Yap, Dr Charlotte Graham, Dr John Maher, King's College Hospital NHS Foundation Trust

CRUK/23/003: pCAR19: Phase 1, open label, dose escalation study evaluating the safety and efficacy of next generation anti-CD19 parallel chimeric antigen receptor T cells (pCAR19) in patients with relapsed/refractory B-cell lymphomas

Prospective Sample Collection Awards

Dr Elizabeth Phillips, Dr Kim Linton, University of Manchester

RADAR sample collection: a randomised phase III study with a PET response-adapted design comparing ABVD +/- ISRT with A2VD +/- ISRT in patients with previously untreated stage IA/IIA Hodgkin lymphoma

November 2022

Clinical Trial Awards

Professor Simon Bailey, Newcastle University

YCMB-LR: Prospective international SIOPE/CONNECT phase-III trial to improve neurocognitive outcomes in young children with low-risk medulloblastoma

Dr Toby Eyre, Oxford University Hospitals NHS Foundation Trust

ZEBRA - Zanubrutinib plus rituximab (Zanu -R) as fixed duration, early intervention versus observation for patients with indolent mantle cell lymphoma: a randomised phase II clinical trial

Experimental Medicine Awards

Professor Gary Middleton, University of Birmingham

KETO-LUNG: Assessing the impact of the adoption of a continuous ketogenic diet on the efficacy of combination chemo-immunotherapy using paclitaxel/carboplatin/pembrolizumab in advanced squamous cell cancer of the lung

Biomarker Project Awards

Professor Timothy Aitman & Professor Duncan McLaren, University of Edinburgh

Investigating the potential of cell-free DNA biomarkers to personalise radiotherapy for prostate cancer

Prospective Sample Collection Awards

Dr Jon Griffin & Professor James Catto, University of Sheffield

Novel markers of response to neoadjuvant chemotherapy in urothelial carcinoma in the GUSTO clinical trial

Dr Kwee Yong, University College London

Understanding tumour resistance and relapse in the RADAR study

Professor Jean Abraham, University of Cambridge

PARTNER Sample Collection (Costed Extension)

June 2023

​​Programme Awards

New Programmes

Professor Katrin Ottersbach, University of Edinburgh

The role of the microenvironment in the initiation and maintenance of infant leukaemia

Dr Ingo Ringshausen, University of Cambridge

Oncogene & tumour suppressor-mediated remodelling of the tumour microenvironment in B cell lymphoproliferative diseases

Professor Simona Parrinello, University College London
Glioblastoma Initiation and Re-initiation

Renewing Programmes

Professor Christian Siebold, University of Oxford

Molecular Mechanisms of Morphogen Signalling in the Tumour Microenvironment

Professor Mark Cragg, Professor Stephen Beers, University of Southampton
Targeting myeloid cells for improved antibody immunotherapy

Professor Ronald Hay, University of Dundee

New players in the targeted degradation of the PML-RARA oncogene by arsenic

Programme Foundation Awards

Dr Christopher Tape, University College London

Treatment Analysis via Individualised Organoid Responses (TAILOR)

Multidisciplinary Project Awards

Dr Ran Yan, Dr John Maher, Dr James Arnold, Prof Erik Arstad, Kings College London

Development of Novel 18F-labelled Molecular Probes for Long-Term CAR T-cell Tracking with Positron Emission Tomography (CART_PET)

Cancer Immunology Project Awards

Professor Jessica Strid, Imperial College London

Contribution of bioactive lipid mediators to inflammation and epithelial cancer development


November 2022

​​Programme Awards

New Programmes

Professor Paul Klenerman & Dr Benjamin Fairfax, University of Oxford

Defining the role of MAIT cells in Cancer Immunotherapy

Renewing Programmes

Professor Laura Machesky, University of Cambridge

Mechanosensing, cytoskeletal control and metabolic demand: how tumour growth and metastasis is fuelled by the microenvironment

Professor Derek Mann & Professor Owen Sansom, Newcastle University

Reprogramming neutrophils to reinvigorate the immunosuppressed HCC microenvironment

Professor Brian Huntly, University of Cambridge 

The role of mutational synergy and oncogenic signalling to chromatin in initiation, maintenance and disease resistance in Acute Myeloid Leukaemia (AML)

Professor Kevin Harrington, Institute of Cancer Research

Strategies for optimised adjuvant immunotherapy following curative-intent radiotherapy or chemoradiotherapy for squamous cell cancer of the head and neck

Professor Steve Clifford, Newcastle University

Biomarker-driven individualisation of medulloblastoma therapy

Professor Karim Labib, University of Dundee

Regulation of metazoan replisome disassembly at stalled replication forks and during mitosis

Programme Foundation Awards

Dr Laura Greaves, Newcastle University

Determining and targeting metabolic vulnerabilities in colorectal cancer

Multidisciplinary Project Awards

Professor Nancy Papalopulu, Professor Robert Clarke & Professor Magnus Rattray, University of Manchester

A dynamical systems approach to understand plasticity and non-genetic heterogeneity in cancer

Dr Benjamin Schumann, Dr Ilaria Malanchi & Dr Paul Huang, Imperial College London

Glycosyltransferase engineering to probe the biology of O-linked protein glycosylation in metastatic breast cancer

May 2023

Project Awards

Professor Peter Murchie, University of Aberdeen
Achieving Self-directed Integrated Cancer Aftercare (ASICA) in melanoma: Optimising the intervention using pilot evidence, assisted intelligence and behavioural science

Professor Shankar Balasubramanian & Professor Rebecca Fitzgerald, University of Cambridge
Evaluation of G-quadruplex profiling for the early detection of oesophageal adenocarcinoma

Dr Ana Rio-Machin & Dr Kevin Rouault-Pierre, Queen Mary University of London 
Deciphering the role of germline variants in the RNA-helicases to improve the early detection and management of familial MDS/AML patients

Dr Professor Richard Shaw & Professor Peter Weightman, University of Liverpool
Clinical and technical validation of infrared absorbance spectra to predict malignant transformation in oral potentially malignant disorders (OPMDs)

Dr Daniel Royston & Professor Jens Rittscher, University of Oxford
Integrating AI-based early detection and assessment of myeloproliferative neoplasms (MPN) into routine clinical pathways

Dr Lizhe Zhuang & Professor Rebecca Fitzgerald, University of Cambridge
Cross-platform study of clonal heterogeneity and microenvironmental niches in initiation and progression of Barrett’s oesophagus and oesophageal adenocarcinoma

Primer Awards

Dr Abish Stephen, Professor Keith Hunter & Dr Geraint Morgan, Queen Mary University of London
Volatile metabolomics for early detection of aerodigestive cancers

Dr Xin Yang, University of Cambridge
Improving endometrial cancer risk prediction for prevention and early detection

Professor David Klenerman & Professor Richard Mair, University of Cambridge
Sensitive detection of P53 aggregates in biofluids  for  the early detection of cancer

Dr Luca Panariello & Dr Adam Creamer, Imperial College London
MagnetoCrisprZyme sensor for quantification of circulating microRNA in primary care settings

Dr Marta Canel, University of Edinburgh
Validating new models to investigate the impact of mutational heterogeneity in the early detection of pancreatic cancer

Professor Neil Hunt, University of York
Ultrafast 2D-IR analysis of liquid biopsies for cancer detection

Dr Marek Palace, Dr Christian von Wagner & Dr Carlos Santos Barea , Liverpool John Moores University
Developing multimodal data-driven art-inspired bowel cancer-screening promotion messages

Dr Ljiljana Fruk, University of Cambridge
Senescence-detecting, urine-based nanobiosensor for early detection of lung cancer

Professor Trevor Graham & Dr Callum Gabbutt, Institute of Cancer Research
Sensitive and specific pan-cancer early detection using fluctuating methylation clocks


November 2022

Programme Awards

Professor Caroline Dive & Dr Phil Crosbie, University of Manchester
Development of a multi-modal liquid biopsy for the early detection of lung cancer

Professor Clare Turnbull, Institute of Cancer Research, Dr David Adams, Wellcome Sanger Institute, and Dr Greg Findlay, The Francis Crick Institute
Defining the compendium of pathogenic germline alleles in cancer susceptibility genes via multiplex assays of variant effect (CG-MAVE)

Project Awards

Dr Jacqueline Shields, King's College London
Exploiting The Lymphatic System For Early Detection And Risk Stratification Biomarkers

Dr James Reading, Professor Sam Janes & Dr Maxine Tran, University College London
A multiomic T cell differentiation index (TEDI) for non-invasive early detection of lung and renal cancer

Primer Awards

Dr Gwen Murphy, Imperial College London
Serologic biomarkers of stomach cancer precursor lesions

Dr James Yarmolinsky, University of Bristol
Using reverse Mendelian randomization to discover novel circulating biomarkers for early detection of cancer

Dr Emma Woodward, University of Manchester
ATLAS - eArly deTection in Li frAumeni Syndrome

Professor Paula Mendes, University of Birmingham
Using superselective glycan-binding nanoparticles to create a clinical assay for early ovarian cancer detection

Dr Patrick Kierkegaard, Imperial College London
Developing an equity-focused Target Product Profile for non-invasive biomarker tests tailored to support mobile testing outreach programmes to reduce cancer inequalities


May 2022

Programme Awards

Professor Fiona Walter, Queen Mary, University of London, & Professor Stephen Pereira, University College London
CANDETECT: Accelerating detection of upper gastro-intestinal (UGI) cancers using a multi- cancer early detection platform in primary care

Project Awards

Professor Sam Janes, Dr Amy Webster and Professor Christina Thirlwell, University College London    
Epi-ASCENT: The epigenetic landscape of screen-detected lung cancers

Dr Rasha Abu-Eid, University of Aberdeen 
Integrating Raman spectroscopy and digital pathology as a novel tool for objective grading of oral epithelial dysplasia

Dr Floor Christie-de Jong, University of Sunderland, & Professor Katie Robb, University of Glasgow
Improving uptake of breast, bowel and cervical cancer screening among Muslim women: a feasibility study of a peer-led, faith-based intervention

Primer Awards

Dr Richard Hopkinson, University of Leicester
Detection of aldehyde cancer biomarkers by harnassing their carcinogenic reactivity

Dr Alexander Oldroyd, University of Manchester   
The MyoScreen Study - Investigating the Utility of Liquid Biopsy as a Method of Early Detection of Idiopathic Inflammatory Myopathy-Associated Cancer

Dr Francesco Boccellato, University of Oxford    
Early detection of gastric cancer by the identification of functional markers driving pre- malignant alterations of the tissue

Dr Lauren Ford, Imperial College London  

Dr James Flanagan, Imperial College London 
Combining diet and symptom management for earlier detection of cancer using transactional data

Dr Samantha Hiu Yan Ip, University of Cambridge    
Investigating transportability of cancer detection models across datasets and time using population-wide electronic health data    

Dr Jennifer Heaney, University of Birmingham  
Improving myeloma diagnosis using a simple rapid test

Dr Denitza Williams, Cardiff University  
Novel decision support intervention to support choice in cervical screening modality

Dr Qiang Wang, University of Edinburgh 
Towards in-vivo in-situ early lung cancer detection using fluorescence lifetime imaging endomicroscopy: a preliminary study on data-driven characterisation of lung cancer using label-free autofluorescence lifetime images on unstained lung cancer tissue

Dr Sarah Haywood-Small, Sheffield Hallam University
Vocs-box breathomics: early detection and diagnosis of mesothelioma

Dr Leonid Nikitenko, University of Hull    
EARLY DIAPAC: EARLY DIAgnosis of PAncreatic Cancer by combined proteomics and genomics testing of pancreatic cyst fluid
Dr Christopher Rowlands, Imperial College London 
Cancer Led Optical Ultrasound Detection    

Dr Christian von Wagner, University College London   
Development and evaluation of a chatbot to support informed choice in the UK Bowel Cancer Screening Programmes

Professor Ferdia Gallagher, University of Cambridge  
Early detection of structural and metabolic changes in small renal masses using advanced MRI to differentiate benign from malignant lesions

Dr Ardhendu Behera, Edge Hill University 
LungHealth AI: Using AI to improve early detection and diagnosis of lung cancer

May 2023

Project Awards

Dr James Yarmolinsky, University of Bristol
Obesity and pancreatic cancer risk: leveraging genetic, observational, and molecular approaches to provide novel insights into causal intermediates to inform cancer prevention

Professor Richard Martin, Professor Jenny Donovan, Professor Freddy Hamdy & Professor David Neal, University of Bristol
Answering key questions needed to inform prostate cancer screening policy: long-term follow-up of the ProtecT (15-year) and CAP (18-year) randomised controlled trials.

Professor Doug Easton, University of Cambridge
Characterisation of novel breast cancer susceptibility genes through large-scale targeted sequencing

Biology to Prevention Awards

Professor Walid Khaled & Dr Sara Pensa, University of Cambridge
Targeting BRCA driven premalignant cellular changes in the breast

Professor Kwee Yong, University College London
Understanding and restoring NK cell (dys)function in smouldering myeloma to optimise intervention strategies to prevent development of multiple myeloma


November 2022

Project Awards

Renewing Programme

Professor Amanda Cross, Imperial College London
Screening, Prevention and Diagnosis of Gastrointestinal Cancer

Project Awards

Professor Chris Cardwell, Queen's University Belfast
Antibiotic use and survival from breast cancer

Dr Jamie Hartmann Boyce & Dr Nicola Lindson, University of Oxford
Synthesising evidence on e-cigarettes: two living systematic reviews exploring their efficacy and safety for smoking cessation, and how to stop using them

Dr Tom Dudding & Dr Barry Main, University of Bristol
Head and neck 5000 – Identifying factors affecting survival and secondary physical effects of treatment at 10 years

Dr Laura Woods, Newcastle University
Developing a screening engagement index (SEI) for England

Dr Toral Gathani, University of Oxford
The Associations of Ethnicity and Breast Cancer


May 2022

Programme Awards

New Programme

Professor Claudia Allemani and Professor Michel Coleman, London School of Hygiene and Tropical Medicine
Global surveillance of cancer survival (CONCORD-4): 20-year trends in survival from 22 adult cancers and all childhood cancers, for patients diagnosed during 2000-2019 or later

Project Awards

Dr Simon Lord and Professor Sarah Blagden, University of Oxford
Exploring metformin’s mechanisms of action in mTP53-driven cancers

Professor Shahid Khan and Professor Simon Rushbrook, Imperial College London
Asp-PSC: Effect of Aspirin on Reducing Cancer in Primary Sclerosing Cholangitis

Dr Crawford Moodie, University of Stirling
The Adult Tobacco Policy Survey: Understanding how smokers and ex-smokers respond to tobacco control policies in the UK

Professor Nicholas Timpson and Dr Vanessa Tan, University of Bristol
Role of directly measured metabolic profile as an intermediate between adiposity and endometrial cancer: triangulation of evidence from independent sources

May 2023

Senior Cancer Research Fellowship

Dr Ivana Bjedov, University College London
Defining novel mechanisms of selective radioprotection to improve cancer radiotherapy

Advanced Clinical Science Fellowship

Dr Amaya Viros, Cancer Research UK Manchester Institute
Melanoma metabolic programmes of metastasis, tropism and immunotherapy response by anatomic site

Senior Cancer Research Fellowship

Dr Andrew Blackford, University of Oxford
Genetic and functional interactions of RecQ helicases in cancer

Career Establishment Award

Dr Mirjana Efremova, Queen Mary, University London
Characterising the cellular state transitions mediating colorectal cancer metastasis

Clinician Scientist Award

Dr Sarah Aitken, University of Cambridge
Identifying image biomarkers in the spatial evolution of liver cancer

Pre-doctoral Research Bursary

Dr Khaylen Mistry, University of East Anglia
Molecular characteristics and outcomes of melanoma in England: a national cohort study

Dr Riccardo Masina, University of Cambridge
Modelling drug response with multi-omics using machine learning in PDTC high-throughput drug screening

Dr Daniele Scotto, University of Nottingham
Characterisation of myeloid-derived suppressor cells as a therapeutic target in glioblastoma multiforme

Dr Georgios Solomou, Cambridge University Hospitals NHS Trust
Delineating glioblastoma cell state transitions during cell invasion using a patient-derived glioblastoma ex vivo organoid model (GBO)

Postdoctoral Research Bursary

Dr Thomas Hubbard, University of Exeter
Investigating the changes in breast cancer post neoadjuvant chemotherapy with Raman Spectroscopy

Dr Akshay Patel, University of Birmingham
Investigating Regulatory B cells as determinants of immune-related adverse events following checkpoint blockade therapy

Dr Robert Morgan, University of Manchester
Exploiting a Living Biobank to develop targeted therapies for platinum-resistant ovarian cancer


November 2022

Career Establishment Award

Dr Barrie Peck, Queen Mary, University of London
Understanding and exploiting Acetyl-CoA metabolism in Small Cell Lung Cancer

Senior Cancer Research Fellowship

Dr Jörg Mansfeld, Institute of Cancer Research
Discovery and functional investigation of how ROS can regulate the cell cycle

Clinician Scientist Fellowship

Dr Ayesha Noorani, Wellcome Sanger Institute 
Mapping the clonal dynamics and somatic mutations of the human oesophagus during disease, development and carcinogenesis

Dr Sung Pil Hong, Imperial College London
Single-cell multi-omic profiling of intratumoral heterogeneity to tackle oesophageal cancer cell adaptation to chemotherapy

Dr Gurdeep Mannu, University of Oxford
Pre-invasive and Invasive breast cancer: from risk factors to optimal treatment


May 2022

Career Establishment Award

Dr Manavendra Pathania, University of Cambridge 
The role of partner mutations in histone-mutant paediatric glioma

Dr Oscar Rueda, University of Cambridge
A statistical dynamic system for breast cancer prognosis and patient monitoring

Senior Cancer Research Fellowship

Dr Sophie Acton, University College London
Harnessing the lymphoid tissue niche to boost anti-tumour immunity 

Clinician Scientist Fellowship

Dr Ehsan Ghorani, Imperial College London 
Deciphering mechanisms of immune dysfunction and immunotherapy sensitivity in gestational trophoblastic neoplasia 

Advanced Clinician Scientist Fellowship

Dr Jyoti Nangalia, Wellcome Sanger Institute
Deciphering timelines and trajectories to blood cancer 

More facts and figures about our research funding

Facts and figures about our research funding

Find out more about how and where we supported research in the last year with our interactive map and infographics.

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Awards funded in FY2021-2022

See list of awards funded in FY2021-2022