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A trial looking at targeted cancer drugs or chemotherapy before surgery for locally advanced bowel cancer (FOXTROT 4)

Overview

Cancer types:

Bowel (colorectal) cancer

Status:

Open

Details

This trial is looking at before surgery for bowel cancer to improve treatment.

It is for people who have all the following:

  • bowel cancer that has spread into the surrounding tissues ()

  • a BRAF change (mutation) called BRAFV600E

  • a plan to have surgery to remove their cancer

Recruitment start: 27 October 2023

Recruitment end: 1 April 2027

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Jenny Seligman

Supported by

Yorkshire Cancer Research

University of Leeds

Pierre Fabre

Merck

The Beatson West of Scotland Cancer Centre

University of Birmingham

Last reviewed: 15 September 2024

CRUK internal database number: 19701

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