Bowel (colorectal) cancer, Colon cancer, Rectal cancer
Open
Phase 2
This trial is looking to see if having pembrolizumab before surgery improves treatment for bowel cancer that has a high risk of coming back.
It is for people who:
are going to have surgery to remove their cancer and
have certain gene changes () in their cancer cells
Recruitment start: 20 July 2022
Recruitment end: 31 March 2026
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Kai-Keen Shiu
Cancer Research UK & UCL Cancer Trials Centre
Merck, Sharp & Dohme
University College London (UCL)
Last reviewed: 9 July 2025
CRUK internal database number: 18561