A trial of pembrolizumab before surgery and with radiotherapy for head and neck cancer (KEYNOTE 689)

Please note

This trial is no longer recruiting patients. We hope to add results when they are available.

Overview

Head and neck cancers, Laryngeal cancer, Mouth and oropharyngeal cancer, Pharyngeal cancer, Secondary cancers

Closed

Phase 3

This trial is for people with stage 3 or stage 4a of the:

Stage 3 or stage 4a means one of the following:

the cancer is bigger than 4cm but has not spread into any lymph nodes or any other part of the body
the cancer is any size but has spread to one lymph node on the same side of the neck as the cancer. And the lymph node is no more than 3cm across
the cancer has grown through the tissues around the lips and mouth

Everyone taking part is going to have treatment for head and neck cancer for the first time.

Recruitment start: 10 January 2019

Recruitment end: 22 September 2023