Radiotherapy For Mouth And Oropharyngeal Cancer
Everyone is different and the side effects vary from person to person. You may not have all of the effects mentioned.
In the video below, people affected by cancer who had radiotherapy discuss the general side effects of radiotherapy. It is 7 minutes and 51 seconds long.
Everyone is different and the side effects vary from person to person. You may not have all of the effects mentioned.
Side effects tend to start a few days after the radiotherapy begins. They gradually get worse during treatment. They can continue to get worse after your treatment ends. It is common to continue to have side effects for 4 to 6 weeks after treatment. Most of the side effects begin to improve after this.
In the video below, people affected by cancer who had head and neck radiotherapy discuss the side effects of radiotherapy. It is 8 minutes and 26 seconds long.
You might feel tired during your treatment. It tends to get worse as the treatment goes on. You might also feel weak and lack energy. Rest when you need to.
Tiredness can carry on for weeks to months after the treatment has finished but it usually improves gradually. Some people can feel very tired and exhausted.
Various things can help you to reduce tiredness and cope with it, such as exercise. Some research has shown that taking gentle exercise can give you more energy. It's important to balance exercise with resting.
Get tips on coping with tiredness
You might feel sick at times. You can have anti sickness medicines. Let your treatment team know if you feel sick.
Find out about ways of controlling sickness
Your skin might go red or darker in the treatment area. You might also get slight redness or darkening on the other side of your body. This is where the radiotherapy beams leave the body.
The red or darker areas can feel sore. Your radiographers will give you advice on washing the area and creams to soothe your skin. The soreness usually goes away within 4 weeks of ending the treatment. But your skin might always be slightly darker in that area.
During your radiotherapy treatment, the skin might break down around the treatment area. Your nurse will use special dressings to cover and protect the area. The area usually heals up over a number of weeks.
Find out about caring for your skin
You may lose your appetite because of radiotherapy. Having a sore, dry mouth can make eating difficult. You may also feel sick because of radiotherapy. This will make you feel less like eating.
Read about tips on what you can do if you have a loss of appetite
Radiotherapy causes hair loss in the area of treatment. It may also cause hair loss where the radiation beam leaves the body (the exit site).
It usually starts to grow back a few weeks after treatment but can be patchy. Ask your radiotherapy team to show you where you will lose your hair.
Mouth problems caused by radiotherapy may include:
It is common to have pain in the mouth or face during and after radiotherapy. Speak to your doctor or specialist nurse if you have pain. They can prescribe painkillers.
During and after treatment, you might have difficulty swallowing.
You may see a speech and language therapist (SLT) before you start treatment if this is likely to affect your swallowing. An SLT can assess your swallowing during and after treatment. They can offer you strategies and advice on improving your swallowing difficulties. They also work with a dietitian if you are finding it difficult to eat.
You can have feeds through a nasogastric tube that goes up your nose and down into your stomach. Or you can have a PEG tube (percutaneous endoscopic gastrostomy tube) that goes through the skin into your stomach. Your nurse or dietician will tell you more about this if you need to have one. They will also show you and your relatives how to give the feeds.
Find out more about tube feeding
Read more about difficulty swallowing and what you can do
Radiotherapy can damage the nerve that controls the muscles that move our mouth. This problem is called trismus. Your doctor, dentist, speech and language therapist, physiotherapist or nurse will give you exercises to help strengthen your muscles and to prevent this from becoming a long term problem.
Your food may taste different. Some people often describe having a metallic taste, but others may lose their taste completely. This can take a while to get better after your treatment has finished. Some people experience long term changes in their sense of taste.
Tips:
Read more about what you can do to help with taste changes
After radiotherapy to treat a head and neck cancer, you are at risk of getting swelling called lymphoedema in your neck or face. Lymphoedema is pronounced lim-fo-dee-ma.
Lymph fluid is in all body tissues. It comes from the tiny blood vessels into the body tissues. Usually, it drains back into the bloodstream through channels called lymph vessels. These are part of the lymphatic system.
A build up of lymph fluid in an area of the body can happen if lymph drainage channels or lymph nodes are blocked, removed, or damaged.
Lymphoedema in the head or neck can also cause symptoms inside your mouth and throat. For example, swelling of your tongue and other parts of your mouth.
Tell your doctor or nurse straight away if you:
have any swelling in the head or neck area or a feeling of fullness or pressure
find it difficult to swallow
have changes in your voice
Lymphoedema is easier to control if treated early. It's important that you are referred to a lymphoedema specialist if you have signs of swelling. This is usually a nurse or physiotherapist.
Read more about lymphoedema in the head and neck area
Unfortunately, it is not possible to cure lymphoedema. But things can be done to reduce the swelling and help you feel better. For example, positioning and lymphoedema exercises can help.
Find out more about lymphoedema and how it is managed
Radiotherapy can cause the underlying tissue to become firmer. This is also called fibrosis. Speak to your radiographer about what you can do to help prevent this from happening.
Your saliva normally forms a protective film over your teeth. Having a permanently dry mouth increases the chance of tooth decay. So, you need to take special care and do regular mouth care throughout the day.
Radiotherapy can sometimes damage the jawbone and break down the bone. This is because radiotherapy can reduce the blood supply to the bone. This is called osteoradionecrosis. This is rare but it can happen months or years after your treatment has finished. Symptoms include pain and swelling in your gums.
Before your radiotherapy, you usually see a specialist dentist. They can remove damaged or broken teeth and make sure your dentures fit properly.
They will also show you how to keep your mouth and teeth clean. You will need to do this during your radiotherapy and for a few months afterward, or sometimes longer.
Chemotherapy combined with radiotherapy can make some side effects worse. Combining these treatments is called chemoradiotherapy.
Last reviewed: 04 Sept 2024
Next review due: 04 Sept 2027
Mouth and oropharyngeal cancer develop when abnormal cells in the mouth and oropharynx divide and grow uncontrollably.
Radiotherapy uses high energy waves similar to x-rays to kill cancer cells. You usually have external beam radiotherapy for mouth and oropharyngeal cancer.
Your treatment depends on where in your mouth or oropharynx your cancer is, the type, how big it is, whether it has spread anywhere else in your body and your general health.
Getting practical and emotional support can help you cope with your diagnosis, and life during and after treatment.

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