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A trial of pembrolizumab and lenvatinib for liver cancer (PRIMER-1)

Overview

Cancer types:

Liver cancer

Status:

Open

Phase:

Phase 2

Details

This trial is looking at giving pembrolizumab and lenvatinib before surgery for people with liver cancer.

It is open to people with a type of liver cancer called hepatocellular carcinoma.

Recruitment start: 28 August 2022

Recruitment end: 31 July 2026

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Tim Meyer

Supported by

University College London (UCL)

Merck, Sharp & Dohme

Cancer Research UK & UCL Cancer Trials Centre

Last reviewed: 29 Jan 2026

CRUK internal database number: 18562

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