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A trial of adavosertib with chemotherapy for ovarian cancer

Overview

Cancer types:

Ovarian cancer, Secondary cancers

Status:

Results

Phase:

Phase 2

Details

This trial looked at adavosertib alongside paclitaxel and carboplatin for ovarian cancer that had come back.

It was for women:

  • who had cancer that had responded to in the past

  • whose cancer cells had a particular change (mutation) in the p53

Adavosertib is also called MK-1775 and AZD1775.

This trial was open for people to join between 2013 and 2014. The team published the results in 2020. There is a link to more information in the ‘Summary of results’ section below.

Recruitment start: 11 February 2013

Recruitment end: 31 July 2014

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Susie Banerjee

Supported by

Experimental Cancer Medicine Centre (ECMC)

Merck Sharp & Dohme Ltd

NIHR Clinical Research Network: Cancer

Last reviewed: 18 March 2024

CRUK internal database number: 10187

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