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A trial of megestrol acetate and letrozole for women with breast cancer (PIONEER)

Overview

Cancer types:

Breast cancer

Status:

Closed

Phase:

Phase 2

Details

This trial is comparing letrozole and megestrol acetate with letrozole on its own before surgery to remove breast cancer. It is for women who:

  • can no longer become pregnant (

  • have breast cancer that is sensitive to the female hormone oestrogen ( or ER positive)

Recruitment start: 20 July 2017

Recruitment end: 31 October 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Richard Baird

Supported by

Anticancer Fund

Cambridge University Hospitals NHS Foundation Trust

Cancer Research UK Cambridge Centre

University of Cambridge

National Institute for Health Research

Last reviewed: 13 August 2024

CRUK internal database number: 15022

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