A trial of chemoradiotherapy with or without pembrolizumab for cervical cancer (KEYNOTE-A18)

Overview

Cancer types:

Cervical cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at pembrolizumab for cervical cancer that had spread into the surrounding tissue and had a high risk of coming back. It was for people who had recently been diagnosed and had not had treatment yet.

People could join the trial between 2020 and 2022. The team published the results in 2024 and 2025.

There is a link to more information in the ‘Summary of results’ section below.

Recruitment start: 9 June 2020

Recruitment end: 15 December 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Susan Lalondrelle

Supported by

Merck Sharp & Dohme Ltd

Last reviewed: 23 Jul 2026

CRUK internal database number: 17441

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