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A trial looking at rilvegostomig and datopotamab deruxtecan for non small cell lung cancer that has spread (TROPION-Lung10)

Overview

Cancer types:

Lung cancer, Non small cell lung cancer (NSCLC), Secondary cancers

Status:

Open

Phase:

Phase 3

Details

This trial is looking at rilvegostomig on its own or with datopotamab deruxtecan for non small cell lung cancer. It is comparing this to .

The trial is for people whose cancer has spread into surrounding tissues or to distant parts of the body. This is or metastatic cancer.

You pronounce rilvegostomig as ril–veh–gost-oh-mig.

You pronounce datopotamab deruxtecan as day-toe-pot-oh-mab deh-rux-tee-can. It is also called Dato-DXd for short.

Recruitment start: 4 July 2024

Recruitment end: 25 August 2027

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Tom Newsom-Davis

Supported by

AstraZeneca

Last reviewed: 2 July 2025

CRUK internal database number: 19891

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