Prostate cancer
Results
Phase 3
This trial was for men with prostate cancer that had spread and was getting worse despite having hormone therapy or having their testicles removed. This is called metastatic castration resistant prostate cancer.
The trial compared pembrolizumab and enzalutamide with a dummy drug (placebo) and enzalutamide.
People could join the trial between 2019 and 2022. The team presented the results at the 2023 ESMO conference.
There is a link to more information in the ‘Summary of results’ section below.
Recruitment start: 21 August 2019
Recruitment end: 10 June 2022
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Johann De Bono
Merck Sharp & Dohme LLC
Last reviewed: 10 Jul 2026
CRUK internal database number: 17103