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A trial looking at pembrolizumab and lenvatinib for head and neck cancers (LEAP-010)

Overview

Cancer types:

Head and neck cancers, Laryngeal cancer, Mouth and oropharyngeal cancer, Nasal and paranasal sinus cancer

Status:

Closed

Phase:

Phase 3

Details

This trial is looking at whether having lenvatinib with pembrolizumab works better than pembrolizumab on its own as a treatment for head and neck cancer.

The trial is open to people who have one of following head and neck cancers:

  • mouth cancer (oral cancer)

  • cancer of the back of the mouth (oropharyngeal cancer) caused by the (HVP)

  • cancer of the voice box (laryngeal cancer)

Recruitment start: 13 July 2020

Recruitment end: 29 July 2022

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Kevin Harrington

Supported by

Merck Sharp & Dohme Ltd

Eisai

Last reviewed: 1 August 2022

CRUK internal database number: 16930

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