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A trial looking at higher doses of chemoradiotherapy for people with locally advanced anal cancer (PLATO ACT5)

Overview

Cancer types:

Anal cancer

Status:

Results

Phase:

Phase 2

Details

This trial compared standard dose chemoradiotherapy with higher doses of chemoradiotherapy. It was for people whose anal cancer was over 5cm long or had spread to their . This is called locally advanced anal cancer.

The trial was supported by Cancer Research UK. It was open for people to join between 2017 and 2023. The team published some early results about side effects in 2023. They plan to publish more results at a later date.

Recruitment start: 1 February 2017

Recruitment end: 31 August 2023

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor David Sebag-Montefiore

Supported by

Cancer Research UK

Leeds Institute of Clinical Trials Research, University of Leeds

Stand Up To Cancer

Other information

This is Cancer Research UK trial number CRUK/15/007.

Last reviewed: 14 December 2023

CRUK internal database number: 14592

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