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A trial looking at avelumab and chemotherapy for bowel cancer (POLEM)

Overview

Cancer types:

Bowel (colorectal) cancer, Colon cancer

Status:

Closed

Phase:

Phase 3

Details

This trial is for people with cancer that started in the large bowel (colon). It is for people who have had surgery and are going to have chemotherapy to lower the chances of the cancer coming back.

Everyone taking part has changes (mutations) in the following :

  • mismatch repair

  • POLE

Recruitment start: 24 August 2018

Recruitment end: 5 January 2021

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Tony Dhillon

Supported by

The Royal Marsden NHS Foundation Trust (GI & Lymphoma Clinical Trials Office)

Merck Serono

Last reviewed: 2 August 2022

CRUK internal database number: 16222

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