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A trial looking at a treatment to improve immunity after a stem cell transplant for blood cancers (ICAT)

Overview

Cancer types:

Acute leukaemia, Acute lymphoblastic leukaemia (ALL), Acute myeloid leukaemia (AML), Blood cancers, Cell type, Chronic leukaemia, Chronic lymphocytic leukaemia (CLL), Chronic myeloid leukaemia (CML), Hodgkin lymphoma, Leukaemia, Lymphoma, Myelodysplastic syndrome (MDS), Myeloma, Non-Hodgkin lymphoma (NHL)

Status:

Results

Phase:

Phase 2

Details

This trial looked at a treatment to help the immune system to start working again after having a stem cell transplant from an unrelated donor. This is an allogeneic stem cell transplant.

It was for people with one of the following cancers:

  • acute lymphoblastic leukaemia

  • acute myeloid leukaemia

  • chronic lymphocytic leukaemia

  • chronic myeloid leukaemia

  • Hodgkin lymphoma

  • non Hodgkin lymphoma

  • myeloma

  • myelodysplastic syndrome (MDS)

This trial was open for people to join between 2014 and 2019. The team published the results in 2022.

Recruitment start: 2 July 2014

Recruitment end: 19 July 2019

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Persis Amrolia

Supported by

Medical Research Council (MRC)

NIHR Clinical Research Network: Cancer

University College London (UCL)

Last reviewed: 12 Apr 2023

CRUK internal database number: 11201

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