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A trial of capivasertib for advanced breast cancer that has become resistant to hormone therapy (FAKTION)

Overview

Cancer types:

Breast cancer

Status:

Results

Phase:

Phase 2

Details

This trial looked at capivasertib (AZD5363) with a hormone therapy drug called fulvestrant.

The trial was for women with breast cancer:

  • who were diagnosed after the menopause and

  • their cancer had spread into tissue surrounding the breast or to another part of the body

Cancer Research UK supported this trial.

This trial was open for women to join between 2015 and 2018. The results were published in 2020. The team published further results in 2022.

Recruitment start: 2 May 2014

Recruitment end: 5 March 2018

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Sacha Howell Dr Robert Jones

Supported by

AstraZeneca

Cancer Research UK

Cardiff University, Centre for Trials Research

Experimental Cancer Medicine Centre (ECMC)

NIHR Clinical Research Network: Cancer

Velindre NHS Trust

Other information

This is Cancer Research UK trial number CRUK/12/044.

Last reviewed: 10 August 2022

CRUK internal database number: 10558

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