Prostate cancer
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This study is looking at the role of gene changes in screening for prostate cancer. It is for men aged 40 to 69 who:
who have a family history of prostate cancer
are of Black African or Black African-Caribbean descent
have a change () that could mean they are at a higher risk of developing prostate cancer
This study follows on from a pilot study that looked at whether this would be a useful area of research. You can read about the PROFILE pilot study.
Recruitment start: 6 February 2015
Recruitment end: 31 December 2026
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Rosalind Eeles
Cancer Research UK
Biomedical Research Council (BRC)
Institute of Cancer Research (ICR)
Movember Foundation
National Institute for Health Research (NIHR)
Prof Eeles Research Fund
Ronald and Rita McAulay Fund
You can contact the PROFILE study team at prostate.research@rmh.nhs.uk
Last reviewed: 29 August 2025
CRUK internal database number: 11931
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