Cancer Research UK logo.
SearchDonate
  • Search

A study to find out if looking at gene changes could be part of prostate cancer screening (PROFILE study)

Overview

Cancer types:

Prostate cancer

Status:

Open

Phase:

Other

Details

This study is looking at the role of gene changes in screening for prostate cancer. It is for men aged 40 to 69 who:

  • who have a family history of prostate cancer

  • are of Black African or Black African-Caribbean descent

  • have a change () that could mean they are at a higher risk of developing prostate cancer

This study follows on from a pilot study that looked at whether this would be a useful area of research. You can read about the PROFILE pilot study.

Recruitment start: 6 February 2015

Recruitment end: 31 December 2030

How to join

Please note: In order to you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Rosalind Eeles

Supported by

Cancer Research UK

Biomedical Research Council (BRC)

Institute of Cancer Research (ICR)

Movember Foundation

National Institute for Health Research (NIHR)

Prof Eeles Research Fund

Ronald and Rita McAulay Fund

Other information

You can contact the PROFILE study team at prostate.research@rmh.nhs.uk

Last reviewed: 04 Mar 2026

CRUK internal database number: 11931

Help and support