A study of pembrolizumab and epacadostat for advanced non small cell lung cancer (KEYNOTE 654)

Overview

Cancer types:

Lung cancer, Non small cell lung cancer (NSCLC), Secondary cancers

Status:

Results

Phase:

Phase 2

Details

This study looked at pembrolizumab and epacadostat as a first treatment for non small cell lung cancer that had spread.

People could join the study between February and July 2018. The team published the results in 2024.

There is a link to more information in the ‘Summary of results’ section below.

Recruitment start: 7 February 2018

Recruitment end: 31 July 2018

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Katy Clarke

Supported by

Merck Sharp & Dohme Ltd

Last reviewed: 16 Jul 2026

CRUK internal database number: 15426

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