A study of bone pain in people with myeloma (BPMM)
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
Cancer type:
Status:
Phase:
This study is looking at bone pain and what causes it in people with myeloma. It is open to people who are having tests to find out if they have myeloma.
More about this trial
Myeloma is a type of blood cancer. It can cause bone pain that can affect how you walk and move around (your mobility). And this can affect your 
.
There has been little research into the causes of the bone pain. Researchers think it might be because of changes in the nerves of the bone.
In this study researchers will look at blood samples and samples. They want to find substances () that might tell them more about the cause of the bone pain.
You fill in a quality of life questionnaire. This will tell the team how the pain is affecting your life.
The main aims of this study are to understand:
- more about bone pain in myeloma
- what causes it
- how it affects quality of life
Who can enter
The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if you at least 18 years old and are having tests to find out if you have myeloma.
Who can’t take part
You cannot join this study if any of these apply. You:
- don’t speak English
- are not well enough
- have recently had chemotherapy for another type of cancer
Trial design
The study team expect 35 people to join this study.
Before finding out you have myeloma
You fill in 8 questionnaires. The questions ask about:
- pain that you have
- what you can do
- what symptoms you have
- how you are feeling
This takes about 1 to 2 hours. You can do it at the hospital or take them home. There is a stamped addressed envelope supplied if you take them home.
Research samples
You give 1 extra blood sample for the study. The team will ask for a small sample of your bone marrow when you have a bone marrow test.
Follow up after finding out you have myeloma
8 months after your diagnosis the team invite you to fill in the questionnaires again. You also give another blood sample.
You don’t have to agree to take part in this follow up. You can still take part in the main study.
People who don’t have myeloma
The team want to collect information from people who don’t have myeloma so they can compare it with those who do. They will keep the information about people who aren’t diagnosed with myeloma.
But you won’t be followed up as part of the study.
Hospital visits
The study team will try and take the samples at the same time you have your routine samples taken.
The team give you the questionnaires at your routine hospital appointments.
Side effects
There are no side effects from taking part in this study.
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Dr Andrew Chantry
Supported by
Sheffield Teaching Hospitals NHS Foundation Trust
IMK Almene Fonden
University of Copenhagen
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
