A study looking at a way of helping men manage the side effects of treatment for prostate cancer (MANCAN)

Please note - this trial is no longer recruiting patients. We hope to add results when they are available.

Cancer type:

Prostate cancer

Status:

Closed

Phase:

Other

This study is looking at helping men to manage hot flushes and night sweats following treatment for prostate cancer.

After treatment for prostate cancer, some men have side effects Open a glossary item such as hot flushes and night sweats . These can affect their quality of life.

As part of standard care, men can talk to specialist nurses and doctors about medical treatments for hot flushes but these often have unwanted side effects Open a glossary item . In this study researchers want to help men manage hot flushes and night sweats using exercises and relaxation techniques.

The aim of this study is to find out if it is possible to help men manage hot flushes and night sweats following treatment for prostate cancer.

Who can enter

You may be able to enter this trial if you

Are having hormone treatment for prostate cancer
Have at least 10 hot flushes or night sweats a week
Are at least 18 years old

You cannot enter this trial if you

Have difficulty reading and understanding English

Trial design

This study will recruit 70 men. It is a randomised trial. The men taking part are put into 2 groups by a computer. Neither you nor your doctor will be able to decide which group you are in.

Everybody taking part has an interview with a researcher, completes a questionnaire about their quality of life and wears a hot flush monitor for up to 48 hours. The monitor attaches to your chest, the research team will explain how it works. It is not painful.

The research team give men in group 1 a detailed booklet with advice and exercises to help with hot flushes, as well as a relaxation CD. The researchers will telephone you 2 and 4 weeks after starting these exercises to ask how you are getting on.

Men in group 2 have standard care. This is access to specialist nurses, doctors and a telephone support help line.

After 4 weeks, men in both groups complete another questionnaire, see a member of the research team and wear the hot flush monitor for up to 48 hours.

After 6 months men in both groups see a member of the research team and complete another questionnaire. At this time the researchers offer the men in group 2 the booklet with advice and exercises to help with hot flushes, as well as a relaxation CD.

Hospital visits

You will need to visit the Health Psychology department of King's College London at Guy's Hospital for this study. Taking part in the study will involve 2 or 3 extra hospital visits. The study team will explain this in more detail.

Side effects

The research team do not expect there to be any side effects from taking part in the study. But you may find it hard to talk about your treatment side effects. If this happens, the researcher will offer to stop the interview and continue at another time.