
"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”
This study is looking at the side effects of 2 different types of surgery.
It is open to people:
Surgery is the main treatment for early stage kidney cancer (up to 7cm) that has not spread.
There are two different types of surgery:
Researchers don’t know which type of surgery is better for people with this type of cancer. This study will compare the two types of surgery to find out which is better. It will also look at how the financial costs compare for people taking part.
The aims of the study are to find out:
The following bullet points are a summary of the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if all of the following apply. You:
Who can’t take part
You cannot join study if any of these apply. You:
It is a randomised study. The study team would like 420 people to take part from the UK.
A computer puts you into 1 of 2 groups. Neither you nor your doctor chooses which group you go into. The groups are:
Your surgical team arrange for you to have surgery at the hospital.
You have the same care everyone having kidney surgery has. After your surgery the study team look at your notes to see they type of surgery you had. The study team then keep in contact with you for 2 years after surgery. This is to:
Quality of life
You fill in questionnaires when you join the study and then:
The questions ask about:
These are quality of life questionnaires.
Making decisions about taking part
The team will also ask a small number of people to take part in telephone or in person interviews to find out how they made decisions about taking part in this study. The team will ask you whether you would like to know more about these interviews. You can say no to this and still take part in the main study.
You don’t have any extra hospital visits while taking part in this study. You have standard NHS care. Your hospital team will explain the surgery to you. Ask them any questions you have.
After your surgery, as part of standard NHS care, you will have regular blood tests to check your kidney function. The study team collect the results of these tests from your medical records. The study team will ask you to have these blood tests done if, for some reason, they are not part of your NHS care. The first one will be done while you are in hospital after your surgery. The team then ask you to have a test at 1 month after your surgery, and then at:
These might be done at the hospital or at your GP surgery.
After surgery, as part of standard NHS care, you are likely to have a kidney every year. The study team collect the results of the scan you have about 2 years after your surgery from your medical records. The study team will not ask you to have scans if your hospital team don’t think you need them.
There is a risk of problems or complications after any operation. The possible side effects while taking part in the study are the same as any kidney cancer surgery. Your surgeon will tell you about the potential risks and benefits of each type of surgery.
Possible side effects of kidney cancer surgery include:
We have more information about kidney cancer surgery.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Professor Naeem Soomro
NIHR Health Technology Assessment (HTA) programme
Newcastle upon Tyne Hospitals NHS Foundation Trust
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040
"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”