Header image for Determine which is a rare cancer clinical trial, you can see doctors testing cancer therapies and a mother of a child suffering of cancer.

DETERMINE is a cutting edge UK national precision medicine trial in rare cancers, testing a range of therapies specifically targeting key genetic changes in cancer cells.

DETERMINE

Patient's referral

1. Patient referral

Contact a local investigator at an actively recruiting DETERMINE site to discuss your patient and initiate a referral.

2. Formal submission

After seeking consent from the patient to share their data, the local investigator will make a formal submission to the DETERMINE Molecular Tumour Board (MTB).

You'll need to provide any relevant clinical and genomic data.

3. Decision

The MTB will aim to return their decision to the local investigator within 5 working days.

The patient will need to sign an informed consent document for the specific treatment arm in the trial.

Participating sites

England

Participant site

Investigator contact

Adult/Paediatric site

Status
The Royal Marsden Hospital NHS Foundation Trust, Surrey Dr Lynley Marshall Paediatric In set up
University Hospital Birmingham NHS Foundation Trust, Birmingham Professor Gary Middleton Adults In set up
The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne Dr Alastair Greystoke Adults / Paediatric RECRUITING
The Christie NHS Foundation Trust, Manchester Dr Matthew Krebs Adults RECRUITING
Churchill Hospital, Oxford,  Dr Sarah Pratap Adults RECRUITING
Addenbrooke's Hospital, Cambridge Dr Bristi Basu Adults / Paediatric RECRUITING
Royal Infirmary, Leicester Dr Olubukola Ayodele Adults In set up
Clatterbridge Cancer Centre, Liverpool Dr Daniel Palmer Adults In set up
Manchester University NHS Foundation Trust, Manchester Dr Guy Makin Paediatric In set up
Southampton General Hospital, Southampton Prof Juliet Gray Adults / Paediatric In set up
University Hospitals Bristol and Weston NHS Foundation Trust, Bristol Dr Antony Ng Adults / Paediatric In set up
University College London Hospitals NHS Foundation Trust, London Professor Martin Forster Adults In set up
Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham Dr Susanne Gatz Paediatric In set up

Participant site

Investigator contact

Adult/Paediatric

Status
Belfast Health and Social Care Trust, Belfast                                                             Professor Vicky Coyle                Adults In set up

 

Participant site

Investigator contact

Adult/Paediatric

Status
Beatson West of Scotland Cancer Centre (NHS Greater Glasgow & Clyde), Glasgow Dr Patricia Roxburgh Adults In set up
Royal Hospital For Children Glasgow (NHS Greater Glasgow & Clyde), Glasgow Dr Milind Ronghe Paediatric In set up

 

Participant site

Investigator contact

Adult/Paediatric

Status
Velindre University NHS Trust, Cardiff                                                                           Dr Robert Jones Adults In set up