"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”
A trial looking at the chemotherapy drug vinflunine for advanced breast cancer
Cancer type:
Status:
Phase:
This trial looked at vinflunine for breast cancer that had spread after treatment with other types of chemotherapy.
The trial was open for people to join between 2009 and 2011. The team published the results in 2018.
More about this trial
Doctors usually treat breast cancer with surgery and other treatments including chemotherapy.
But sometimes the cancer comes back (recurs) or spreads to another part of the body. When this happens, doctors often give one of a group of chemotherapy drugs called
Researchers wanted to find out if vinflunine would be useful. This is a different type of chemotherapy drug.
The people taking part in this trial were put into a treatment group at random:
- half had vinflunine
- half had an alkylating drug
The main aims of this trial were to find out:
- if vinflunine works better than an alkylating drug for advanced breast cancer
- how treatment affects
quality of life
Summary of results
As part of our editorial policy, any trial information we write is checked externally before we put it on our website. The research team have published some results for this trial. But we have been unable to find anyone involved with the trial to check a summary for us.
This means we are not able to include a plain English summary of the results on this page.
More information
There is more information about this trial in the link to the medical journal below.
Please note, the information we link to here is not in plain English. It has been written for healthcare professionals and researchers.
Open-label randomised phase III trial of vinflunine versus an alkylating agent in patients with heavily pretreated metastatic breast cancer
J Cortes and others
Annals of Oncology, 2018. Volume 29, issue 4, pages 881-887.
Recruitment start:
Recruitment end:
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Chief Investigator
Dr Martin Hogg
Supported by
NIHR Clinical Research Network: Cancer
Pierre Fabre Medicament
If you have questions about the trial please contact our cancer information nurses
Freephone 0808 800 4040