A trial of pembrolizumab and chemotherapy for cancer of the stomach and cancer where the food pipe joins the stomach (KEYNOTE 859)

Overview

Cancer types:

Oesophageal cancer, Secondary cancers, Stomach cancer

Status:

Closed

Phase:

Phase 3

Details

This trial is for people with stomach cancer or cancer where the food pipe joins the stomach (gastro oesophageal junction). It is for people whose cancer:

  • has grown into the surrounding tissues (locally advanced) or spread to other parts of the body (advanced)

  • doesn’t have a large amount of proteins called HER2 on its surface (HER2 negative)

You can’t join this trial if your cancer has a large amount of HER2 proteins on its surface (HER2 positive). We have information about a trial looking at pembrolizumab and chemotherapy for people with HER2 positive stomach or gastro oesophageal junction cancer.

Recruitment start: 18 January 2018

Recruitment end: 15 April 2021

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Kai-Keen Shiu

Supported by

Merck Sharp & Dohme Ltd

Last reviewed: 03 May 2021

CRUK internal database number: 16044

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