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A trial of olaparib and cediranib after platinum chemotherapy for ovarian cancer that has come back (ICON9)

Overview

Cancer types:

Ovarian cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at olaparib and cediranib after chemotherapy for ovarian cancer that had started to grow again after initial treatment.

It was for women who had:

  • ovarian cancer

  • fallopian tube cancer

  • primary peritoneal cancer

Doctors treat these cancers in the same way. So, when we use the term ovarian cancer in this summary, we are referring to all 3.

This trial was supported by Cancer Research UK. It was open for women to join between 2018 and 2023. The team presented the first set of results at a conference in 2024.

Recruitment start: 1 August 2018

Recruitment end: 20 February 2023

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Shibani Nicum

Supported by

Cancer Research UK

AstraZeneca

University College London

Stand Up To Cancer

Gynecologic Cancer InterGroup

Canadian Cancer Trials Group (CCTG)

Australia New Zealand Gynaecological Oncology Group (ANZGOG)

European Network of Gynaecological Oncology Trials groups (ENGOT)

National Cancer Research Institute (NCRI)

Other information

This is Cancer Research UK trial number CRUK/15/074.

Last reviewed: 11 September 2025

CRUK internal database number: 13388

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