A trial of targeted drugs for chronic myeloid leukaemia when treatment has stopped working (TASTER)

Cancer type:

Blood cancers
Chronic leukaemia
Chronic myeloid leukaemia (CML)




Phase 2

This trial was for people with chronic myeloid leukaemia. It looked at adding a targeted drug to the targeted drug people were already taking. 

It was open to people with chronic myeloid leukaemia (CML):

Cancer Research UK supported this trial.

More about this trial

When this trial was done, doctors could  treat chronic myeloid leukaemia (CML) with one of the following:

These targeted drugs Open a glossary item are cancer growth blockers called tyrosine kinase inhibitors (TKIs). Tyrosine kinase is a protein that acts as a messenger to stimulate cancer cells to grow. TKIs block these messages.

Sometimes these drugs stop working. So researchers were looking for other drugs to help people in this situation. In this trial, they are looked at other TKI's
The aims of this trial were to find out:

  • how well adding a newer drug works
  • what the side effects are 
  • how it affects quality of life Open a glossary item

Summary of results

There aren't any results available for this trial. This was because it closed earlier than planned as it was difficult to recruit patients to take part. 

Recruitment start:

Recruitment end:

How to join a clinical trial

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Chief Investigator

Professor Mhairi Copland

Supported by

Cancer Research UK
University of Glasgow
NHS Greater Glasgow and Clyde

Other information

This is Cancer Research UK trial number CRUK/17/016.

If you have questions about the trial please contact our cancer information nurses

Freephone 0808 800 4040

Last review date

CRUK internal database number:


Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.

Last reviewed:

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