A trial of T-VEC and pembrolizumab for advanced melanoma (MASTERKEY-265)

Overview

Cancer types:

Melanoma, Skin cancer

Status:

Results

Phase:

Phase 3

Details

This trial looked at T-VEC and pembrolizumab for people with melanoma skin cancer. It was for people whose melanoma could not be removed with surgery. The full name for T-VEC is talimogene laherparepvec.

People could join the trial between 2016 and 2018. The team published the results in 2022.

Recruitment start: 17 March 2016

Recruitment end: 26 April 2018

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Kevin Harrington

Supported by

Amgen

Experimental Cancer Medicine Centre (ECMC)

Last reviewed: 01 Jun 2026

CRUK internal database number: 13832

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