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A trial of radiotherapy and targeted treatment for head and neck cancer (ADePT-DDR)

Overview

Cancer types:

Head and neck cancers, Laryngeal cancer, Mouth and oropharyngeal cancer, Pharyngeal cancer

Status:

Open

Phase:

Phase 1/2

Details

This trial is looking at adding certain targeted drugs to radiotherapy for head and neck cancer. Some parts of the trial are also looking at these treatments with immunotherapy.

The trial is for people who have one of the following types of head and neck cancer:

  • oropharyngeal cancer

  • cancer of the area that surrounds the voice box ()

  • cancer of the voice box (laryngeal cancer)

18055 ADePT-DDR - Trial Diagram.

Recruitment start: 5 September 2021

Recruitment end: 5 January 2026

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Anthony Kong

Supported by

AstraZeneca

University of Birmingham

Last reviewed: 24 Sept 2025

CRUK internal database number: 18055

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