A trial of LEQ506 for advanced cancer that has got worse despite other treatment

Please note

This trial is no longer recruiting patients. We hope to add results when they are available.

Overview

Cancer types:

All cancer types

Status:

Closed

Phase:

Phase 1

Details

This trial is looking at a drug called LEQ506 for advanced solid tumours. A solid tumour is any type of cancer apart from or .

Cells normally grow in a very orderly way. Chemical messages or signals tell them when to grow and when to stop. But in cancer cells the normal signalling system changes. So the cells keep on dividing. The cancer grows and may spread to other parts of the body.

LEQ506 is a new drug that blocks a specific protein and stops it sending growth signals. We know from research that blocking this protein affects the growth of several types of cancer cells. But this is the first time LEQ506 is being tested in people.

The people taking part have that has got worse despite having other treatments. The aims of the trial are to