A trial of CXD101 and nivolumab for a certain type of advanced bowel cancer (CAROSELL)

Please note

This trial is no longer recruiting patients. We hope to add results when they are available.

Overview

Cancer types:

Bowel (colorectal) cancer, Secondary cancers

Status:

Closed

Phase:

Phase 1/2

Details

This trial is looking at a new drug called CXD101 alongside nivolumab for bowel cancer that has spread elsewhere in the body.

It is for people who have a certain type of bowel cancer called microsatellite stable.

Bowel cancers have different types of changes in the DNA. A small number of bowel cancers have DNA changes called microsatellite instability. Most bowel cancers do not have these changes and are called microsatellite stable. This is the most common type of advanced bowel cancer.

Recruitment start: 22 May 2018

Recruitment end: 22 May 2019