
"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”
Please note - this trial is no longer recruiting patients. We hope to add results when they are available.
This trial is looking at a to help prevent infections in children who are having or have recently finished treatment for acute lymphoblastic leukaemia (ALL).
The trial is for children and young people up to and including the age of 18. We use the term ‘you’ in this summary, but if you are a parent, we are referring to your child.
Chemotherapy can affect your , which helps to fight infection. Doctors know that children having chemotherapy for ALL are at increased risk of an infection called pneumococcus. In this trial doctors want to use a new vaccine to help protect against pneumococcal infection.
The aim of this study is to find out if a new vaccine can help prevent pneumococcal infection in children who are having or have just finished treatment for ALL.
You may be able to enter this trial if you
You cannot enter this trial if you
This trial will recruit 120 people from the UK. There are 3 treatment groups. Each group has the same vaccine. The vaccine is an injection into your thigh or arm muscle. You have 1 vaccination and are on the trial for a year.
This study does not affect your cancer treatment and you see your cancer doctors while you are on the study.
You will see the doctors and have some tests before you have the vaccine. The tests include
The study nurse will see you 1 month after your vaccination for blood tests and to see how you are. You see the study nurse again a year after the vaccination for blood tests and swabs of your nose and throat. This is the end of the trial.
The most common side effects of the vaccination are pain, swelling, tenderness and redness where you had the injection. This will go after 1 or 2 days.
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Juliet Gray
NIHR Clinical Research Network: Cancer
NIHR Research for Patient Benefit (RfPB) Programme
University Hospital Southampton NHS Foundation Trust
Freephone 0808 800 4040
"I was delighted to take part in a clinical trial as it has the potential to really help others in the future.”