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A trial looking at ruxolitinib to treat polycythaemia vera and essential thrombocythaemia (MAJIC)

Overview

Cancer types:

Blood cancers, Polycythaemia, Thrombocythaemia

Status:

Results

Phase:

Phase 2

Details

This trial looked at a drug called ruxolitinib to treat high risk polycythaemia vera (PV) and high risk essential thrombocythaemia (ET).

Polycythaemia vera and essential thrombocythaemia are . These are conditions in which the makes too many blood cells. In PV it is too many and in ET it is too many . These conditions are closely related to .

This trial closed in 2016. These results published in 2017 are for essential thrombocythemia. The trial team will publish the results of polycythaemia vera at a later date. When these results are published we will update this summary.

Recruitment start: 1 August 2012

Recruitment end: 31 July 2016

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Prof Claire Harrison

Supported by

Bloodwise

Cambridge Blood and Stem Cell Biobank

Experimental Cancer Medicine Centre (ECMC)

Guy's and St Thomas' NHS Foundation Trust

Mayo Clinic

NIHR Clinical Research Network: Cancer

Novartis

University of Birmingham

Last reviewed: 22 Jul 2018

CRUK internal database number: 9306

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