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A trial looking at nemtabrutinib, ibrutinib or acalabrutinib for chronic lymphocytic leukaemia or small lymphocytic lymphoma (BELLWAVE-011)

Overview

Cancer types:

Blood cancers, Chronic leukaemia, Chronic lymphocytic leukaemia (CLL), Leukaemia, Low grade lymphoma, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Open

Phase:

Phase 3

Details

This trial is comparing nemtabrutinib with ibrutinib or acalabrutinib for chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL).

It is for people who haven’t yet had treatment for CLL or SLL.

You pronounce nemtabrutinib as nem-ta-broo-ti-nib.

Recruitment start: 26 January 2024

Recruitment end: 19 July 2027

How to join

Please note: In order to you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Toby Eyre

Supported by

Merck Sharp & Dohme Ltd

Last reviewed: 27 Nov 2025

CRUK internal database number: 19841

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