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A trial looking at lenalidomide for B cell chronic lymphocytic leukaemia in elderly people (The ORIGIN Trial)

Overview

Cancer types:

Blood cancers, Chronic leukaemia, Chronic lymphocytic leukaemia (CLL), Leukaemia

Status:

Closed

Phase:

Phase 3

Details

This trial is looking at lenalidomide (Revlimid) as treatment for B cell chronic lymphocytic leukaemia (B cell CLL) in elderly people. This trial is open to people with B cell CLL aged 65 years or older.

Doctors often treat B cell CLL with chlorambucil, which is a chemotherapy drug. This trial is looking at comparing chlorambucil with lenalidomide.

Lenalidomide is a biological therapy. It mainly works by helping the body’s immune system target cancer cells.

The aims of this trial are to compare lenalidomide with chlorambucil to treat elderly people with B cell CLL.

Recruitment start: 11 November 2009

Recruitment end: 20 February 2013

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr David Oscier

Supported by

Celgene Corporation

Experimental Cancer Medicine Centre (ECMC)

Last reviewed: 27 Feb 2013

CRUK internal database number: 7874

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