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A trial looking at lenalidomide after chemotherapy for T cell lymphoma of the skin

Overview

Cancer types:

Cell type, Low grade lymphoma, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Results

Phase:

Phase 3

Details

This trial was looking at lenalidomide after treatment with chemotherapy for advanced T cell lymphoma of the skin.

T cell lymphomas of the skin (CTCL) are types of non Hodgkin lymphoma. Mycosis fungoides and Sezary syndrome are the most common types of T cell skin lymphomas, although they are still rare.

Doctors usually treat advanced T cell lymphoma of the skin with chemotherapy drugs called gemcitabine or liposomal doxorubicin. You may also have radiotherapy.

Chemotherapy often shrinks or gets rid of the cancer but sadly it can start to grow again. Doctors are looking for treatments to help people in this situation. In this trial they were testing a drug called lenalidomide.

Lenalidomide is a type of biological therapy. It works mainly by helping the body’s immune system target cancer cells.

Doctors wanted to find out

  • If having lenalidomide after chemotherapy could prevent or delay the cancer coming back

  • More about the side effects

Recruitment start: 3 May 2011

Recruitment end: 2 September 2013

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Sean Whittaker

Supported by

European Organisation for Research and Treatment of Cancer (EORTC)

Experimental Cancer Medicine Centre (ECMC)

NIHR Clinical Research Network: Cancer

Last reviewed: 16 Apr 2015

CRUK internal database number: 8747

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