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A trial looking at lapatinib, trastuzumab and chemotherapy before surgery for breast cancer (LAPATAX) (EORTC 10054)

Overview

Cancer types:

Breast cancer

Status:

Results

Phase:

Phase 2

Details

This trial looked at lapatinib, trastuzumab and chemotherapy before surgery for breast cancer. The trial was for women who have HER2 positive breast cancer. This means the cancer has large amounts of a protein called .

If your breast cancer has spread into the surrounding tissue (is ), is inflammatory breast cancer or you have a large tumour, you may have chemotherapy before surgery. If your breast cancer is also HER2 positive you may have trastuzumab (Herceptin) before surgery.

Although this works well doctors are always looking for ways to improve treatment.

Recruitment start: 1 May 2011

Recruitment end: 31 January 2013

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Prof David Cameron

Supported by

European Organisation for Research and Treatment of Cancer (EORTC)

Experimental Cancer Medicine Centre (ECMC)

GlaxoSmithKline (GSK)

NIHR Clinical Research Network: Cancer

Last reviewed: 07 Oct 2015

CRUK internal database number: 9380

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