“I think it’s really important that people keep signing up to these type of trials to push research forward.”
A trial looking at treatment for children and young people with low grade glioma brain tumours (SIOP – LGG 2004 CNS 2004 03)
This trial looked at adding etoposide to the standard chemotherapy treatment for children and young people with a type of brain tumour called low grade glioma.
It was for children and young people, up to the age of 16, who had a low grade tumour. A low grade tumour means that it usually grows very slowly.
Cancer Research UK supported this trial.
More about this trial
Summary of results
- 249 children and young people had vincristine and carboplatin (VC group)
- 248 children and young people had vincristine, carboplatin and etoposide (VCE group)
- 3 children the cancer disappeared (
- 59 children the cancer shrunk to at least half the size (
- 36 children the cancer shrunk to at least a third, but no more than half the size (improvement)
- 98 children the cancer stayed the same (
- 15 children the cancer got worse (
- 3 children the cancer disappeared
- 50 children the cancer shrunk to at least half the size
- 33 children the cancer shrunk to at least a third, but no more than half the size
- 106 children the cancer stayed the same
- 18 children the cancer got worse
How to join a clinical trial
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Sue Picton
Prof David Walker
Cancer Research UK
Cancer Research UK Children's Cancer Trials Team
University of Birmingham
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
This is Cancer Research UK trial number CRUK/05/012.