“I think it’s really important that people keep signing up to these type of trials to push research forward.”
A trial looking at treatment for children and young people with low grade glioma brain tumours (SIOP – LGG 2004 CNS 2004 03)
This trial looked at adding etoposide to the standard chemotherapy treatment for children and young people with a type of brain tumour called low grade glioma.
It was for children and young people, up to the age of 16, who had a low grade tumour. A low grade tumour means that it usually grows very slowly.
Cancer Research UK supported this trial.
More about this trial
Summary of results
- 249 children and young people had vincristine and carboplatin (VC group)
- 248 children and young people had vincristine, carboplatin and etoposide (VCE group)
- 3 children the cancer disappeared (
- 59 children the cancer shrunk to at least half the size (
- 36 children the cancer shrunk to at least a third, but no more than half the size (improvement)
- 98 children the cancer stayed the same (
- 15 children the cancer got worse (
- 3 children the cancer disappeared
- 50 children the cancer shrunk to at least half the size
- 33 children the cancer shrunk to at least a third, but no more than half the size
- 106 children the cancer stayed the same
- 18 children the cancer got worse
How to join a clinical trial
Dr Sue Picton
Prof David Walker
Cancer Research UK
Cancer Research UK Children's Cancer Trials Team
University of Birmingham
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
This is Cancer Research UK trial number CRUK/05/012.