"I am glad that taking part in a trial might help others on their own cancer journey.”
A trial looking at chemotherapy and panitumumab before surgery for bowel cancer (FOxTROT)
We know that this is an especially worrying time for people with cancer and their family and friends. We have separate information about coronavirus and cancer. Please read that information alongside this page. We will update that information as guidance changes.
This trial looked at whether having chemotherapy and panitumumab before surgery helps stop bowel cancer coming back. It was supported by Cancer Research UK.
More about this trial
- if having some chemotherapy before surgery helps stop bowel cancer coming back
- if panitumumab helps stop bowel cancer coming back in people with normal RAS genes
Summary of results
- Group A – 555 people had chemotherapy, then surgery and then more chemotherapy
- Group B – 143 people had chemotherapy and panitumumab, then surgery and then more chemotherapy
- Group C - 354 people had surgery and then chemotherapy
- more than 1 out of 10 people (14%) who’d had treatment before and after surgery
- just less than 2 out of 10 people (18%) who’d had treatment after surgery but not before
- 33 people (5%) who’d had treatment before surgery
- 34 people (10%) who hadn’t had treatment before surgery
How to join a clinical trial
Prof Dion Morton
Bobby Moore Fund (BMF)
Cancer Research UK
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
This is Cancer Research UK trial number CRUK/07/014.