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A trial looking at celecoxib with standard treatment for certain types of cancer that have spread (LION Trial)

Overview

Cancer types:

Breast cancer, Kidney cancer, Lung cancer, Non small cell lung cancer (NSCLC), Renal cell cancer, Secondary cancers

Status:

Open

Phase:

Phase 2

Details

This trial is looking at adding a drug called celecoxib to standard treatment to improve treatment for advanced cancer. This is cancer that has spread into surrounding tissues or to another part of the body.

It is for people who are having their first treatment for advanced:

  • triple negative breast cancer

  • non small cell lung cancer

  • renal cell cancer

Recruitment start: 8 May 2024

Recruitment end: 1 December 2025

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Anne Armstrong

Supported by

The Christie NHS Foundation Trust

The Jon Moulton Charity Trust

The Christie Charity

Liverpool Clinical Trials Centre

Last reviewed: 15 Apr 2025

CRUK internal database number: 19932

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