A trial looking at AZD5363 and enzalutamide for advanced prostate cancer (RE-AKT)

This trial is looking at AZD5363 and enzalutamide for men with prostate cancer that has spread and continued to grow despite having other treatment.

Doctors usually treat advanced prostate cancer with hormone therapy and chemotherapy. These can work well for a period of time, but the cancer can start to grow again.

Enzalutamide is a type of hormone therapy that is used for men with advanced prostate cancer who have already had other types of hormone therapy and a type of chemotherapy called docetaxel. Researchers want to see if a having a new drug called AZD5363 alongside enzalutamide will help to control the growth of cancer for longer.