A trial looking at a different way of giving a drug combination called MATRix for people with primary lymphoma of the brain and spinal cord (OptiMATe)

This trial is looking at a different way of giving a combination of drugs called MATRix. It is for people with primary lymphoma of the brain and spinal cord. This is also called primary CNS lymphoma.

This trial is open to people who are newly diagnosed with primary CNS lymphoma:

• that is a large Diffuse B cell lymphoma

• and are due to have MATRix followed by an autologous stem cell transplant