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A trial looking at abiraterone with exemestane for breast cancer that has spread

Overview

Cancer types:

Breast cancer

Status:

Closed

Phase:

Phase 2

Details

This trial is looking at using a new drug called abiraterone with exemestane for breast cancer that has spread to another part of the body. This trial is for women who have oestrogen receptor positive (ER positive) breast cancer.

Doctors often use hormone therapy to treat breast cancer. Two drugs they use are anastrozole and letrozole. But sometimes the cancer starts to grow again and then doctors may use exemestane.

Abiraterone is a new type of hormone therapy. It stops the body from making certain hormones. The researchers think that using abiraterone with exemestane may be better than exemestane alone.

The aim of this trial is to compare exemestane alone with abiraterone and exemestane. The researchers want to find out which is best for women whose breast cancer has continued to grow during or after treatment with anastrozole or letrozole.

Recruitment start: 1 October 2011

Recruitment end: 15 April 2013

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Andreas Makris

Supported by

Experimental Cancer Medicine Centre (ECMC)

Janssen-Cilag

National Institute for Health Research Cancer Research Network (NCRN)

Last reviewed: 14 Apr 2013

CRUK internal database number: 8403

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