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A trial looking at lenalidomide for mantle cell lymphoma (EMERGE)

Overview

Cancer types:

Blood cancers, Cell type, Low grade lymphoma, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Results

Phase:

Phase 2

Details

This trial looked at lenalidomide for people who had mantle cell non Hodgkin lymphoma. It was for people who had been treated with bortezomib (Velcade).

Doctors often treat mantle cell lymphoma with chemotherapy. If mantle cell lymphoma comes back, doctors are not sure what to treat it with and have few treatments to choose from.

Bortezomib is a type of biological therapy. It is a cancer growth blocker. It stops signals that cancer cells use to divide and grow. Doctors only give bortezomib to people with mantle cell lymphoma as a part of clinical trials.

Lenalidomide is another type of biological therapy. It works mainly by helping the body’s immune system target cancer cells.

The aims of this trial were to find out

  • If lenalidomide could help people with mantle cell lymphoma after having bortezomib

  • How safe it was to give lenalidomide to people with mantle cell lymphoma after having bortezomib

Recruitment start: 6 January 2009

Recruitment end: 26 March 2012

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Dr Anton Kruger

Supported by

Celgene Corporation

Last reviewed: 21 May 2014

CRUK internal database number: 6149

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