Bowel (colorectal) cancer, Colon cancer
Open
Phase 3
This trial is comparing a combination of 2 chemotherapy drugs with a combination of 3 chemotherapy drugs for bowel cancer. It is comparing these combinations before and after surgery.
The trial is for people:
whose cancer has grown into surrounding tissue (locally advanced cancer)
who can have surgery to remove the cancer
who are well enough to have the combination of 3 chemotherapy drugs
Please note, if you aren’t suitable for this trial, you might be able to take part in the FOXTROT 2 trial for bowel cancer. We have a summary of FOXTROT 2 on our trials database.
Recruitment start: 7 February 2022
Recruitment end: 7 February 2027
Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.
Dr Jenny Seligmann
University of Leeds
Yorkshire Cancer Research
University of Birmingham
Last reviewed: 10 Jan 2025
CRUK internal database number: 18362
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