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A trial of bortezomib with R-CHOP for diffuse large B cell lymphoma (REMoDL-B)

Overview

Cancer types:

Blood cancers, Cell type, High grade lymphoma, Lymphoma, Non-Hodgkin lymphoma (NHL)

Status:

Results

Phase:

Phase 3

Details

This trial was done to see if bortezomib can help stop diffuse large B cell lymphoma coming back after treatment. It was for people who hadn’t had treatment for their lymphoma before.

The trial was supported by Cancer Research UK.

It was open for people to join between 2011 and 2015. The team published the results in 2019 and 2023.

Recruitment start: 17 May 2011

Recruitment end: 12 June 2015

How to join

Please note: In order to join a trial you will need to discuss it with your doctor, unless otherwise specified.

Chief investigators

Professor Peter Johnson

Supported by

Cancer Research UK

Experimental Cancer Medicine Centre (ECMC)

Janssen-Cilag

NIHR Clinical Research Network: Cancer

University Hospital Southampton NHS Foundation Trust

University of Southampton

Other information

This is Cancer Research UK trial number CRUKE/10/024.

Last reviewed: 3 June 2025

CRUK internal database number: 6190

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