Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study to find out more about the causes of lung cancer (ReSoLuCENT)
This study collected information to help find out more about possible causes of lung cancer that are related to people’s genetic make up or lifestyle.
More about this trial
There are several known risk factors for lung cancer. Smoking is the most significant. But there are other factors that may increase or decrease risk.
In this study, the research team collected blood samples and information about genetic changes and lifestyle from people with lung cancer, and their partners and relatives.
The research team looked at the information in the questionnaires and the genetic material (DNA) in the blood samples. They hoped to find out which lifestyle factors and genetic changes are important in the development of lung cancer.
The aim of this study was to set up a store of information about genetic and lifestyle factors for people with lung cancer and their partners and relatives. This will help the researchers find out more about what causes lung cancer and what doesn’t.
Summary of results
- be more heavily addicted to nicotine
- find it more difficult to give up smoking
- develop lung cancer at an earlier age
- an increased level of low density lipoprotein (LDL) cholesterol in their blood had a reduced risk of developing lung cancer
- an increased level of insulin in their blood had an increased risk of developing lung cancer
How to join a clinical trial
Professor P Woll
Experimental Cancer Medicine Centre (ECMC)
NIHR Clinical Research Network: Cancer
Weston Park Cancer Charity
Sheffield Hospitals Charity