Around 1 in 5 people diagnosed with cancer in the UK take part in a clinical trial.
A study to collect blood samples and tissue samples to look at the genes of early lung cancer detected through screening (ASCENT)
This study is collecting blood and tissue samples from people diagnosed with lung cancer. It is also for people suspected of having lung cancer. It is open to people who took part in the SUMMIT study.
More about this trial
The SUMMIT study is looking at using low dose
In this study the team take blood samples. They also take a piece of the lung tissue that the surgeon removes during surgery. They use these samples to look at the
They also look at the results of any scans or tests you have from the time of screening to surgery. The team want to see if they can identify patterns that might suggest lung cancer. Their hope is that by doing this in the future doctors might be able to better understand and diagnose lung cancer.
Please note you won’t get any direct benefit from taking part. The researchers hope that what they learn from this study might help doctors improve the diagnosis of lung cancer.
Who can enter
The following bullet points list the entry conditions for this study. Talk to your doctor or the study team if you are unsure about any of these. They will be able to advise you.
Who can take part
You may be able to join this study if you are taking part in the SUMMIT study and all of the following apply. You:
- have lung cancer or might have lung cancer
- are to have or have had surgery to remove the cancer
Who can’t take part
You cannot join this study if any of these apply. You:
- are to have chemotherapy or radiotherapy to shrink the cancer before surgery (neo adjuvant treatment)
- have an active infection of HIV, hepatitis B, hepatitis C or syphilis
The study team need 336 people who took part in the SUMMIT study to join.
You give 4 samples of blood. You give these on the day you have surgery.
The team take a small sample of the tissue (
They use these samples to look at the
There are no extra hospital visits in this study.
There are no side effects apart from some possible slight bleeding or bruising from the blood samples.
How to join a clinical trial
Professor Sam Janes
Cancer Research UK
University College London (UCL)
National Institute for Health Research (NIHR)